OBJECTIVE: The hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery are debated. The aim of the present study was to quantify cardiac output and left ventricular chamber volumes after vacuum-assisted closure using magnetic resonance imaging, which is known to be the most accurate method for quantifying these measures. METHODS: Six pigs had median sternotomy followed by vacuum-assisted closure treatment in the presence and absence of a paraffin gauze interface dressing. Cardiac output and stroke volume were examined using magnetic resonance imaging flow quantification (breath-hold and real-time). Chamber volumes were assessed using cine magnetic resonance imaging. RESULTS: Cardiac output and stroke volume decreased immediately after application of negative pressures of 75, 125, and 175 mm Hg (13% +/- 1% decrease in cardiac output). Interposition of 4 layers of paraffin gauze dressing over the heart during vacuum-assisted closure therapy resulted in a smaller decrease in cardiac output (8% +/- 1%). CONCLUSIONS: Vacuum-assisted closure therapy results in an immediate decrease in cardiac output, although to a lesser extent than shown previously. Covering the heart with a wound interface dressing lessens the hemodynamic effects of vacuum-assisted closure.
OBJECTIVE: The hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery are debated. The aim of the present study was to quantify cardiac output and left ventricular chamber volumes after vacuum-assisted closure using magnetic resonance imaging, which is known to be the most accurate method for quantifying these measures. METHODS: Six pigs had median sternotomy followed by vacuum-assisted closure treatment in the presence and absence of a paraffin gauze interface dressing. Cardiac output and stroke volume were examined using magnetic resonance imaging flow quantification (breath-hold and real-time). Chamber volumes were assessed using cine magnetic resonance imaging. RESULTS: Cardiac output and stroke volume decreased immediately after application of negative pressures of 75, 125, and 175 mm Hg (13% +/- 1% decrease in cardiac output). Interposition of 4 layers of paraffin gauze dressing over the heart during vacuum-assisted closure therapy resulted in a smaller decrease in cardiac output (8% +/- 1%). CONCLUSIONS: Vacuum-assisted closure therapy results in an immediate decrease in cardiac output, although to a lesser extent than shown previously. Covering the heart with a wound interface dressing lessens the hemodynamic effects of vacuum-assisted closure.
Authors: Christian Torbrand; Martin Ugander; Henrik Engblom; Göran K Olivecrona; Olof Gålne; Håkan Arheden; Richard Ingemansson; Malin Malmsjö Journal: Int Wound J Date: 2010-08 Impact factor: 3.315
Authors: Christian Torbrand; Martin Ugander; Henrik Engblom; Göran K Olivecrona; Olof Gålne; Håkan Arheden; Richard Ingemansson; Malin Malmsjö Journal: Int Wound J Date: 2010-04 Impact factor: 3.315
Authors: Christian Torbrand; Richard Ingemansson; Lotta Gustafsson; Per Paulsson; Malin Malmsjö Journal: Int Wound J Date: 2008-09-19 Impact factor: 3.315
Authors: Einar Heiberg; Jane Sjögren; Martin Ugander; Marcus Carlsson; Henrik Engblom; Håkan Arheden Journal: BMC Med Imaging Date: 2010-01-11 Impact factor: 1.930