Literature DB >> 21173189

Characterization of the Novel CMT Enzyme TEM-154.

Frédéric Robin1, Julien Delmas, Elisabete Machado, Bernadette Bouchon, Luísa Peixe, Richard Bonnet.   

Abstract

TEM-154, identified in Portugal in 2004, associated the substitutions observed in the extended-spectrum β-lactamase (ESBL) TEM-12 and in the inhibitor-resistant penicillinase (IRT) TEM-33. This enzyme exhibited hydrolytic activity against ceftazidime and a low level of resistance to clavulanic acid. Surprisingly, the substitution Met69Leu enhanced the catalytic efficiency of oxyimino β-lactams conferred by the substitution Arg164Ser. Its discovery confirms the dissemination of the complex mutant group of TEM enzymes in European countries.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 21173189      PMCID： PMC3067075          DOI： 10.1128/AAC.01359-10

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  Updated sequence information and proposed nomenclature for bla(TEM) genes and their promoters.

Authors:  V Leflon-Guibout; B Heym; M Nicolas-Chanoine
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

2.  TEM-89 beta-lactamase produced by a Proteus mirabilis clinical isolate: new complex mutant (CMT 3) with mutations in both TEM-59 (IRT-17) and TEM-3.

Authors:  C Neuwirth; S Madec; E Siebor; A Pechinot; J M Duez; M Pruneaux; M Fouchereau-Peron; A Kazmierczak; R Labia
Journal:  Antimicrob Agents Chemother       Date:  2001-12       Impact factor: 5.191

Review 3.  Inhibitor-resistant TEM beta-lactamases: phenotypic, genetic and biochemical characteristics.

Authors:  E B Chaïbi; D Sirot; G Paul; R Labia
Journal:  J Antimicrob Chemother       Date:  1999-04       Impact factor: 5.790

4.  A complex mutant of TEM-1 beta-lactamase with mutations encountered in both IRT-4 and extended-spectrum TEM-15, produced by an Escherichia coli clinical isolate.

Authors:  D Sirot; C Recule; E B Chaibi; L Bret; J Croize; C Chanal-Claris; R Labia; J Sirot
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

5.  Novel plasmid-mediated beta-lactamase in clinical isolates of Klebsiella pneumoniae more resistant to ceftazidime than to other broad-spectrum cephalosporins.

Authors:  A Petit; D L Sirot; C M Chanal; J L Sirot; R Labia; G Gerbaud; R A Cluzel
Journal:  Antimicrob Agents Chemother       Date:  1988-05       Impact factor: 5.191

6.  Computerized microacidimetric determination of beta lactamase Michaelis-Menten constants.

Authors:  R Labia; J Andrillon; F Le Goffic
Journal:  FEBS Lett       Date:  1973-06-15       Impact factor: 4.124

7.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

Review 8.  A functional classification scheme for beta-lactamases and its correlation with molecular structure.

Authors:  K Bush; G A Jacoby; A A Medeiros
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191

9.  Sequences of CAZ-3 and CTX-2 extended-spectrum beta-lactamase genes.

Authors:  C Chanal; D Sirot; H Malaure; M C Poupart; J Sirot
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

10.  Rapid procedure for detection and isolation of large and small plasmids.

Authors:  C I Kado; S T Liu
Journal:  J Bacteriol       Date:  1981-03       Impact factor: 3.490
View more
  3 in total

1.  CTX-M-190, a Novel β-Lactamase Resistant to Tazobactam and Sulbactam, Identified in an Escherichia coli Clinical Isolate.

Authors:  Zhen Shen; Baixing Ding; Yingmin Bi; Shi Wu; Su Xu; Xiaogang Xu; Qinglan Guo; Minggui Wang
Journal:  Antimicrob Agents Chemother       Date:  2016-12-27       Impact factor: 5.191

2.  In Vivo Evolution of CTX-M-215, a Novel Narrow-Spectrum β-Lactamase in an Escherichia coli Clinical Isolate Conferring Resistance to Mecillinam.

Authors:  Minggui Wang; Qinglan Guo; Mengyun Yin; Guoping Hu; Zhen Shen; Chengli Fang; Xuefei Zhang; Dan Li; Yohei Doi; Yu Zhang
Journal:  Antimicrob Agents Chemother       Date:  2020-10-20       Impact factor: 5.191

3.  Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.

Authors:  Rainer Hartl; Heidrun Kerschner; Sarah Lepuschitz; Werner Ruppitsch; Franz Allerberger; Petra Apfalter
Journal:  Antimicrob Agents Chemother       Date:  2017-03-24       Impact factor: 5.191
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.