Literature DB >> 2115331

Stimulated platelets release amyloid beta-protein precursor.

G M Cole1, D Galasko, I P Shapiro, T Saitoh.   

Abstract

Human platelets can be stimulated by thrombin or ionomycin to secrete soluble truncated amyloid beta-protein precursor and particulate membrane fragments which contain C-terminal and N-terminal immunoreactive amyloid beta-protein precursor. This suggests a possible circulating source of beta-protein in serum which may play a role in the formation of amyloid deposits. The release of soluble amyloid beta-protein precursor could be involved in normal platelet physiology.

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Year:  1990        PMID： 2115331      PMCID： PMC4019003          DOI： 10.1016/0006-291x(90)91272-t

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  31 in total

1.  Isolation of human platelets from plasma by centrifugation and washing.

Authors:  J F Mustard; R L Kinlough-Rathbone; M A Packham
Journal:  Methods Enzymol       Date:  1989       Impact factor: 1.600

2.  Amyloid beta protein precursor is possibly a heparan sulfate proteoglycan core protein.

Authors:  D Schubert; R Schroeder; M LaCorbiere; T Saitoh; G Cole
Journal:  Science       Date:  1988-07-08       Impact factor: 47.728

3.  Family study of platelet membrane fluidity in Alzheimer's disease.

Authors:  G S Zubenko; M Wusylko; B M Cohen; F Boller; I Teply
Journal:  Science       Date:  1987-10-23       Impact factor: 47.728

4.  The presence of contractile proteins in platelet microparticles isolated from human and animal platelet-free plasma.

Authors:  N Crawford
Journal:  Br J Haematol       Date:  1971-07       Impact factor: 6.998

5.  Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity.

Authors:  N Kitaguchi; Y Takahashi; Y Tokushima; S Shiojiri; H Ito
Journal:  Nature       Date:  1988-02-11       Impact factor: 49.962

6.  An antiserum against amyloid beta-protein precursor detects a unique peptide in Alzheimer brain.

Authors:  G Cole; E Masliah; T V Huynh; R DeTeresa; R D Terry; C Okuda; T Saitoh
Journal:  Neurosci Lett       Date:  1989-05-22       Impact factor: 3.046

7.  Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

Authors:  B Rumble; R Retallack; C Hilbich; G Simms; G Multhaup; R Martins; A Hockey; P Montgomery; K Beyreuther; C L Masters
Journal:  N Engl J Med       Date:  1989-06-01       Impact factor: 91.245

8.  Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals.

Authors:  F Tagliavini; G Giaccone; B Frangione; O Bugiani
Journal:  Neurosci Lett       Date:  1988-11-11       Impact factor: 3.046

9.  Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate.

Authors:  D Schubert; M LaCorbiere; T Saitoh; G Cole
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

10.  Cytosolic ionized calcium and bleb formation after acute cell injury of cultured rabbit renal tubule cells.

Authors:  P C Phelps; M W Smith; B F Trump
Journal:  Lab Invest       Date:  1989-05       Impact factor: 5.662
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  10 in total

1.  Effects of staurosporine, U-73122, wortmannin, 4-hydroxynonenal and sodium azide upon the release of secreted beta-amyloid precursor protein from human platelets in response to thrombin stimulation.

Authors:  H L Hedin; L Nilsson; C J Fowler
Journal:  Mol Cell Biochem       Date:  2001-03       Impact factor: 3.396

2.  Endothelium-specific amyloid precursor protein deficiency causes endothelial dysfunction in cerebral arteries.

Authors:  Livius V d'Uscio; Tongrong He; Anantha V Santhanam; Zvonimir S Katusic
Journal:  J Cereb Blood Flow Metab       Date:  2017-09-29       Impact factor: 6.200

Review 3.  Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium.

Authors:  Livius V d'Uscio; Tongrong He; Zvonimir S Katusic
Journal:  Physiology (Bethesda)       Date:  2017-01

Review 4.  The role of beta-amyloid peptide in Alzheimer's disease.

Authors:  A LeBlanc
Journal:  Metab Brain Dis       Date:  1994-03       Impact factor: 3.584

5.  Deficiency of fibrinolytic enzyme activities in the serum of patients with Alzheimer-type dementia.

Authors:  T Aoyagi; T Wada; F Kojima; M Nagai; S Harada; T Takeuchi; K Isse; M Ogura; M Hamamoto; K Tanaka
Journal:  Experientia       Date:  1992-07-15

6.  Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels.

Authors:  A Tamaoka; R N Kalaria; I Lieberburg; D J Selkoe
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-15       Impact factor: 11.205

7.  A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion.

Authors:  J Ghiso; A Rostagno; J E Gardella; L Liem; P D Gorevic; B Frangione
Journal:  Biochem J       Date:  1992-12-15       Impact factor: 3.857

Review 8.  Microvascular pathology and vascular basement membrane components in Alzheimer's disease.

Authors:  L S Perlmutter
Journal:  Mol Neurobiol       Date:  1994 Aug-Dec       Impact factor: 5.590

Review 9.  Cross-species and interassay comparisons of phytoestrogen action.

Authors:  P L Whitten; H B Patisaul
Journal:  Environ Health Perspect       Date:  2001-03       Impact factor: 9.031

10.  Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth.

Authors:  H Ninomiya; J M Roch; M P Sundsmo; D A Otero; T Saitoh
Journal:  J Cell Biol       Date:  1993-05       Impact factor: 10.539
  10 in total

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