Literature DB >> 21132812

Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain.

David R J Owen1, Andrew J M Lewis, Richard Reynolds, Rainer Rupprecht, Daniela Eser, Martin R Wilkins, Idriss Bennacef, David J Nutt, Christine A Parker.   

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Year:  2011        PMID： 21132812     DOI： 10.1002/syn.20884

Source DB:  PubMed          Journal:  Synapse        ISSN： 0887-4476            Impact factor:   2.562


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  19 in total

Review 1.  Translocator protein (18 kDa): an update on its function in steroidogenesis.

Authors:  V Papadopoulos; J Fan; B Zirkin
Journal:  J Neuroendocrinol       Date:  2018-02       Impact factor: 3.627

Review 2.  Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition.

Authors:  Borwin Bandelow; David Baldwin; Marianna Abelli; Blanca Bolea-Alamanac; Michel Bourin; Samuel R Chamberlain; Eduardo Cinosi; Simon Davies; Katharina Domschke; Naomi Fineberg; Edna Grünblatt; Marek Jarema; Yong-Ku Kim; Eduard Maron; Vasileios Masdrakis; Olya Mikova; David Nutt; Stefano Pallanti; Stefano Pini; Andreas Ströhle; Florence Thibaut; Matilde M Vaghi; Eunsoo Won; Dirk Wedekind; Adam Wichniak; Jade Woolley; Peter Zwanzger; Peter Riederer
Journal:  World J Biol Psychiatry       Date:  2016-07-15       Impact factor: 4.132

3.  11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than 11C-( R)-PK11195.

Authors:  Masato Kobayashi; Teresa Jiang; Sanjay Telu; Sami S Zoghbi; Roger N Gunn; Eugenii A Rabiner; David R Owen; Qi Guo; Victor W Pike; Robert B Innis; Masahiro Fujita
Journal:  J Cereb Blood Flow Metab       Date:  2017-03-21       Impact factor: 6.200

4.  Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism.

Authors:  Jing Gong; Éva M Szego; Andrei Leonov; Eva Benito; Stefan Becker; Andre Fischer; Markus Zweckstetter; Tiago Outeiro; Anja Schneider
Journal:  J Neurosci       Date:  2019-02-22       Impact factor: 6.167

Review 5.  The changing landscape in translocator protein (TSPO) function.

Authors:  Vimal Selvaraj; Douglas M Stocco
Journal:  Trends Endocrinol Metab       Date:  2015-03-21       Impact factor: 12.015

Review 6.  50 years of hurdles and hope in anxiolytic drug discovery.

Authors:  Guy Griebel; Andrew Holmes
Journal:  Nat Rev Drug Discov       Date:  2013-09       Impact factor: 84.694

7.  Functional TSPO polymorphism predicts variance in the diurnal cortisol rhythm in bipolar disorder.

Authors:  Alan R Prossin; Matthew Chandler; Kelly A Ryan; Erika F Saunders; Masoud Kamali; Vassilios Papadopoulos; Sebastian Zöllner; Robert Dantzer; Melvin G McInnis
Journal:  Psychoneuroendocrinology       Date:  2018-01-31       Impact factor: 4.905

8.  Structural Integrity of the A147T Polymorph of Mammalian TSPO.

Authors:  Mariusz Jaremko; Łukasz Jaremko; Karin Giller; Stefan Becker; Markus Zweckstetter
Journal:  Chembiochem       Date:  2015-06-10       Impact factor: 3.164

9.  Detection of Alzheimer's disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein.

Authors:  Bin Ji; Maiko Ono; Tomoteru Yamasaki; Masayuki Fujinaga; Ming-Rong Zhang; Chie Seki; Ichio Aoki; Seiji Kito; Makoto Sawada; Tetsuya Suhara; Naruhiko Sahara; Makoto Higuchi
Journal:  J Cereb Blood Flow Metab       Date:  2021-02-08       Impact factor: 6.200

10.  Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study.

Authors:  David R Owen; Qi Guo; Nicola J Kalk; Alessandro Colasanti; Dimitra Kalogiannopoulou; Rahul Dimber; Yvonne L Lewis; Vincenzo Libri; Julien Barletta; Joaquim Ramada-Magalhaes; Aruloly Kamalakaran; David J Nutt; Jan Passchier; Paul M Matthews; Roger N Gunn; Eugenii A Rabiner
Journal:  J Cereb Blood Flow Metab       Date:  2014-03-19       Impact factor: 6.200
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