Literature DB >> 211201

Noradrenaline receptor sensitivity after chronic ethanol administration.

S Liljequist, N E Andén, J Engel, M Henning.   

Abstract

The effects of the central noradrenaline receptor stimulating agent clonidine on blood pressure, heart rate, and flexor reflex activity were studied in intact rats and in rats chronically treated with ethanol. The clonidine-induced changes were similar in ethanol-treated animals and in animals never subjected to ethanol. The results suggest that the sensitivity of central noradrenaline receptors involved in the mediation of the circulatory changes and of the flexor reflex activity after clonidine is not altered by chronic administration of ethanol.

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Year:  1978        PMID： 211201     DOI： 10.1007/bf02029015

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  17 in total

1.  Involvement of alpha-adrenergic receptors at different levels of the central nervous system in the regulation of blood pressure and heart frequency.

Authors:  G G Trolin
Journal:  Acta Physiol Scand Suppl       Date:  1975

2.  Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents.

Authors:  N E Andén; M Grabowska; U Strömbom
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976       Impact factor: 3.000

3.  The effect of chronic ethanol administration on the levels of catecholamines in different regions of the rat brain.

Authors:  M E Post; A Y Sun
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1973-11

4.  Alterations in the turnover of brain norepinephrine and dopamine in alcohol-dependent rats.

Authors:  W A Hunt; E Majchrowicz
Journal:  J Neurochem       Date:  1974-09       Impact factor: 5.372

5.  Investigations into the mechanism of the hypotensive effect of 2-(2,6-dichlorphenylamino)-2-imidazoline-HCl.

Authors:  W Kobinger; A Walland
Journal:  Eur J Pharmacol       Date:  1967-12       Impact factor: 4.432

6.  The effect of long-term ethanol treatment on the sensitivity of the dopamine receptors in the nucleus accumbens.

Authors:  J Engel; S Liljequist
Journal:  Psychopharmacology (Berl)       Date:  1976-09-29       Impact factor: 4.530

7.  Action of -adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine.

Authors:  H Schmitt; S Fénard
Journal:  Arzneimittelforschung       Date:  1973-01

8.  Brain concentrations of biogenic amine metabolites in acutely treated and ethanol-dependent rats.

Authors:  F Karoum; R J Wyatt; E Majchrowicz
Journal:  Br J Pharmacol       Date:  1976-04       Impact factor: 8.739

9.  Changes in monoamine concentrations in mouse brain associated with ethanol dependence and withdrawal.

Authors:  P J Griffiths; J M Littleton; A Ortiz
Journal:  Br J Pharmacol       Date:  1974-04       Impact factor: 8.739

10.  Changes in the sensitivity of dopamine receptors in the nucleus accumbens and in the striatum induced by chronic ethanol administration.

Authors:  S Liljequist
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1978-07
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  1 in total

1.  Attenuation of the gamma-butyrolactone-induced increase in DOPA accumulation by chronic ethanol administration.

Authors:  S Liljequist; J Engel
Journal:  J Neural Transm       Date:  1979       Impact factor: 3.575
  1 in total

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