| Literature DB >> 4475606 |
P J Griffiths, J M Littleton, A Ortiz.
Abstract
1 Chronic administration of ethanol to mice by inhalation induced tolerance to ethanol and produced an increase in the concentration of brain monoamines.2 Withdrawal of ethanol from dependent mice caused behavioural changes associated with a further transient rise in brain monoamine concentrations which then declined to control levels.3 Inhibition of the withdrawal syndrome by the administration of ethanol postponed the changes in monoamines associated with withdrawal.4 Administration of inhibitors of catecholamine synthesis before withdrawal of ethanol modified the withdrawal syndrome.Entities:
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Year: 1974 PMID： 4475606 PMCID： PMC1776724 DOI： 10.1111/j.1476-5381.1974.tb08582.x
Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739