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Literature DB >> 528994

Attenuation of the gamma-butyrolactone-induced increase in DOPA accumulation by chronic ethanol administration.

Abstract

The effect of gamma-butyrolactone (GBL) on the accumulation of dopa after inhibition of aromatic amino acid decarboxylase was studied in rats following chronic treatment with ethanol. The GBL-induced dopa accumulation was significantly decreased in ethanol-treated rats. With the increased duration of the ethanol treatment this effect appears to be more marked in the limbic forebrain. It is suggested that chronic ethanol treatment may produce a decreased sensitivity of central GABA receptors.

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Year: 1979 PMID： 528994 DOI： 10.1007/BF01250785

Source DB: PubMed Journal: J Neural Transm Impact factor: 3.575

22 in total

1. The effect of intracerebroventricularly administered GABA on brain monoamine metabolism.

Authors: B Biswas; A Carlsson
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1977-08 Impact factor: 3.000

2. Influence of GABA and GABA-like drugs on monoaminergic mechanisms.

Authors: A Carlsson; B Biswas; M Lindqvist
Journal: Adv Biochem Psychopharmacol Date: 1977

3. Effect of pentobarbitone and diethyl ether on the synthesis of monoamines in rat brain.

Authors: M Lindqvist; W Kehr; A Carlsson
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1974 Impact factor: 3.000

4. Increase in brain dopamine after axotomy or treatment with gammahydroxybutyric acid due to elimination of the nerve impulse flow.

Authors: G Stock; T Magnusson; N E Andén
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1973 Impact factor: 3.000

5. Effects of acute and chronic ethanol on the gamma-amino-butyric acid system in rat brain.

Authors: U Sutton; M A Simmonds
Journal: Biochem Pharmacol Date: 1973-07-15 Impact factor: 5.858

6. Effect of anesthetic doses of hydroxybutyrate on subcortical concentrations of homovanillic acid.

Authors: R H Roth
Journal: Eur J Pharmacol Date: 1971-06 Impact factor: 4.432

7. A procedure for the isolation of noradrenaline (together with adrenaline), dopamine, 5-hydroxytryptamine and histamine from the same tissue sample using a single column of strongly acidic cation exchange resin.

Authors: C Atack; T Magnusson
Journal: Acta Pharmacol Toxicol (Copenh) Date: 1978-01

Attenuation of the gamma-butyrolactone-induced increase in DOPA accumulation by chronic ethanol administration.

1. The effect of intracerebroventricularly administered GABA on brain monoamine metabolism.

2. Influence of GABA and GABA-like drugs on monoaminergic mechanisms.

3. Effect of pentobarbitone and diethyl ether on the synthesis of monoamines in rat brain.

4. Increase in brain dopamine after axotomy or treatment with gammahydroxybutyric acid due to elimination of the nerve impulse flow.

5. Effects of acute and chronic ethanol on the gamma-amino-butyric acid system in rat brain.

6. Effect of anesthetic doses of hydroxybutyrate on subcortical concentrations of homovanillic acid.

7. A procedure for the isolation of noradrenaline (together with adrenaline), dopamine, 5-hydroxytryptamine and histamine from the same tissue sample using a single column of strongly acidic cation exchange resin.

8. The effect of long-term ethanol treatment on the sensitivity of the dopamine receptors in the nucleus accumbens.

Review 9. Some aspects of dopamine in the central nervous system.

10. Suppression of ethanol-induced locomotor stimulation by GABA-like drugs.

1. [Effect of ethanol on the neurotransmitters glutamate and GABA].

2. The stimulus properties of gamma-hydroxybutyrate.