INTRODUCTION: Achalasia is a rare esophageal motility disorder, incurable but amenable to palliative treatments to relieve dysphagia. Given the rarity of the disease, there is a paucity of data from population-based studies on incidence and outcome of the two treatments most commonly used in clinical practice, i.e., endoscopic pneumatic dilation (PD) and surgical myotomy (SM). MATERIALS AND METHODS: A retrospective longitudinal study was conducted on the Veneto region, in north-eastern Italy. All patients with achalasia as their primary diagnosis between 2001 and 2005 were identified and their demographics and treatment details obtained. RESULTS: The overall incidence of achalasia was 1.59 cases/100,000/year. Achalasia patients were mainly seen at University Hospitals. Fifty-five percent of the patients received treatment, 23.3% SM and 31.8% PD. The cumulative risk of any subsequent intervention for achalasia was 20% in treated patients (29.7% in patients treated primarily with PD and 4% in patients treated with SM first). DISCUSSION: The epidemiology of achalasia in the Veneto Region is in line with the situation reported elsewhere and did not change between 2001 and 2005. Achalasia patients are mostly seen at University Hospitals. We observed a greater risk of subsequent intervention for patients previously treated with PD compared with SM.
INTRODUCTION:Achalasia is a rare esophageal motility disorder, incurable but amenable to palliative treatments to relieve dysphagia. Given the rarity of the disease, there is a paucity of data from population-based studies on incidence and outcome of the two treatments most commonly used in clinical practice, i.e., endoscopic pneumatic dilation (PD) and surgical myotomy (SM). MATERIALS AND METHODS: A retrospective longitudinal study was conducted on the Veneto region, in north-eastern Italy. All patients with achalasia as their primary diagnosis between 2001 and 2005 were identified and their demographics and treatment details obtained. RESULTS: The overall incidence of achalasia was 1.59 cases/100,000/year. Achalasiapatients were mainly seen at University Hospitals. Fifty-five percent of the patients received treatment, 23.3% SM and 31.8% PD. The cumulative risk of any subsequent intervention for achalasia was 20% in treated patients (29.7% in patients treated primarily with PD and 4% in patients treated with SM first). DISCUSSION: The epidemiology of achalasia in the Veneto Region is in line with the situation reported elsewhere and did not change between 2001 and 2005. Achalasiapatients are mostly seen at University Hospitals. We observed a greater risk of subsequent intervention for patients previously treated with PD compared with SM.
Authors: Giovanni Zaninotto; Mario Costantini; Christian Rizzetto; Lisa Zanatta; Emanuela Guirroli; Giuseppe Portale; Loredana Nicoletti; Francesco Cavallin; Giorgio Battaglia; Alberto Ruol; Ermanno Ancona Journal: Ann Surg Date: 2008-12 Impact factor: 12.969
Authors: Renato Salvador; Mario Costantini; Francesco Cavallin; Lisa Zanatta; Elena Finotti; Cristina Longo; Loredana Nicoletti; Giovanni Capovilla; Romeo Bardini; Giovanni Zaninotto Journal: J Gastrointest Surg Date: 2013-09-10 Impact factor: 3.452
Authors: Salih Samo; Dustin A Carlson; Dyanna L Gregory; Susan H Gawel; John E Pandolfino; Peter J Kahrilas Journal: Clin Gastroenterol Hepatol Date: 2016-08-28 Impact factor: 11.382
Authors: Helen G Coleman; Ronan T Gray; Kar W Lau; Conall McCaughey; Peter V Coyle; Liam J Murray; Brian T Johnston Journal: World J Gastroenterol Date: 2016-04-21 Impact factor: 5.742