Literature DB >> 21095581

The meaning of pausing.

Joaquín M Espinosa1.   

Abstract

Pausing of RNA polymerase II (RNAPII) at the 5' end of genes is a widespread phenomenon in metazoans, but the role of this event in gene regulation is poorly understood. Gilchrist et al. (2010) now demonstrate that RNAPII pausing counteracts DNA-influenced nucleosome organization to allow precise gene activation.
Copyright © 2010 Elsevier Inc. All rights reserved.

Year:  2010        PMID： 21095581     DOI： 10.1016/j.molcel.2010.11.025

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  5 in total

1.  Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.

Authors:  Iván D'Orso; Gwendolyn M Jang; Alexander W Pastuszak; Tyler B Faust; Elizabeth Quezada; David S Booth; Alan D Frankel
Journal:  Mol Cell Biol       Date:  2012-09-24       Impact factor: 4.272

Review 2.  Unravelling the means to an end: RNA polymerase II transcription termination.

Authors:  Jason N Kuehner; Erika L Pearson; Claire Moore
Journal:  Nat Rev Mol Cell Biol       Date:  2011-04-13       Impact factor: 94.444

3.  Promoter-proximal CCCTC-factor binding is associated with an increase in the transcriptional pausing index.

Authors:  Sur Herrera Paredes; Michael F Melgar; Praveen Sethupathy
Journal:  Bioinformatics       Date:  2012-10-09       Impact factor: 6.937

4.  Discovery of active enhancers through bidirectional expression of short transcripts.

Authors:  Michael F Melgar; Francis S Collins; Praveen Sethupathy
Journal:  Genome Biol       Date:  2011-11-14       Impact factor: 13.583

Review 5.  Transcriptional regulation by hypoxia inducible factors.

Authors:  Veronica L Dengler; Matthew Galbraith; Joaquín M Espinosa
Journal:  Crit Rev Biochem Mol Biol       Date:  2013-10-07       Impact factor: 8.250
  5 in total

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