OBJECTIVE: To determine the prevalence of and the risk factors for wheezing in infants under one year of age and residing in the city of Porto Alegre, Brazil. METHODS: This was a cross-sectional study and is part of a multicenter, multinational project. The parents or legal guardians of the infants were interviewed at primary health care clinics or during home visits. We used a standardized questionnaire, validated for use in Brazil. Potential risk factors were assessed by means of a Poisson regression model with robust variance estimation, using the Wald test to determine the significance of each variable in the model. RESULTS: The sample comprised 1,013 infants. The majority of those were male (53%), and the mean age was 13.5 ± 1.2 months. In 61% of the infants, there had been at least one episode of wheezing, which had recurred at least three times in one third of those infants. The mean age at the first episode of wheezing was 5.16 months (median, 5 months). Over 40% of the infants with wheezing visited emergency rooms due to wheezing, and 17% of those were hospitalized at least once in the first year of life because of this symptom. In the multivariate analysis, the risk factors for wheezing were as follows: male gender; history of pneumonia; maternal smoking during pregnancy; day care center attendance; low maternal level of education; early weaning; multiple episodes of cold; first viral infection prior to 3 months of age; existence of siblings; and history of asthma in the nuclear family. CONCLUSIONS: The prevalence of wheezing is high among infants in the city of Porto Alegre. We identified various risk factors for wheezing in infants.
OBJECTIVE: To determine the prevalence of and the risk factors for wheezing in infants under one year of age and residing in the city of Porto Alegre, Brazil. METHODS: This was a cross-sectional study and is part of a multicenter, multinational project. The parents or legal guardians of the infants were interviewed at primary health care clinics or during home visits. We used a standardized questionnaire, validated for use in Brazil. Potential risk factors were assessed by means of a Poisson regression model with robust variance estimation, using the Wald test to determine the significance of each variable in the model. RESULTS: The sample comprised 1,013 infants. The majority of those were male (53%), and the mean age was 13.5 ± 1.2 months. In 61% of the infants, there had been at least one episode of wheezing, which had recurred at least three times in one third of those infants. The mean age at the first episode of wheezing was 5.16 months (median, 5 months). Over 40% of the infants with wheezing visited emergency rooms due to wheezing, and 17% of those were hospitalized at least once in the first year of life because of this symptom. In the multivariate analysis, the risk factors for wheezing were as follows: male gender; history of pneumonia; maternal smoking during pregnancy; day care center attendance; low maternal level of education; early weaning; multiple episodes of cold; first viral infection prior to 3 months of age; existence of siblings; and history of asthma in the nuclear family. CONCLUSIONS: The prevalence of wheezing is high among infants in the city of Porto Alegre. We identified various risk factors for wheezing in infants.
Authors: Hamilton Rosendo Fogaça; Fernando Augusto de Lima Marson; Adyléia Aparecida Dalbo Contrera Toro; Dirceu Solé; José Dirceu Ribeiro Journal: J Bras Pneumol Date: 2014 Nov-Dec Impact factor: 2.624
Authors: Carolina Sanchez Aranda; Gustavo Falbo Wandalsen; Ana Caroline Cavalcanti Dela Bianca; Ellen de Oliveira Dantas; Javier Mallol; Dirceu Solé Journal: Rev Paul Pediatr Date: 2018 Oct-Dec
Authors: Wellington Fernando da Silva Ferreira; Denise Siqueira de Carvalho; Gustavo Falbo Wandalsen; Dirceu Solé; Emanuel Sávio Cavalcante Sarinho; Décio Medeiros; Ana Carolina Cavalcanti Dela Bianca Melo; Elaine Xavier Prestes; Paulo Augusto Moreira Camargos; Karin Regina Luhm; Luis Garcia-Marcos; Javier Mallol; Nelson Augusto Rosário; Herberto José Chong-Neto Journal: J Pediatr (Rio J) Date: 2021-02-07 Impact factor: 2.990