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Literature DB >> 21079591

Grand challenge commentary: The chemistry of a dynamic genome.

Abstract

In the postsequencing era, chemical biology is uniquely situated to investigate genomic DNA alterations arising through epigenetic modifications, genetic rearrangements or active mutation. These transformations significantly expand nature's diversity and may profoundly alter our view of DNA's coding potential.

Mesh：

Substances：
DNA

Year: 2010 PMID： 21079591 DOI： 10.1038/nchembio.471

Source DB: PubMed Journal: Nat Chem Biol ISSN： 1552-4450 Impact factor: 15.040

20 in total

Review 1. A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V.

Authors: Meghna Patel; Qingfei Jiang; Roger Woodgate; Michael M Cox; Myron F Goodman
Journal: Crit Rev Biochem Mol Biol Date: 2010-06 Impact factor: 8.250

Review 2. Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation.

Authors: Peter A Smith; Floyd E Romesberg
Journal: Nat Chem Biol Date: 2007-09 Impact factor: 15.040

3. Small-molecule inhibition of HIV-1 Vif.

Authors: Robin Nathans; Hong Cao; Natalia Sharova; Akbar Ali; Mark Sharkey; Ruzena Stranska; Mario Stevenson; Tariq M Rana
Journal: Nat Biotechnol Date: 2008-09-21 Impact factor: 54.908

Review 4. The colorful history of active DNA demethylation.

Authors: Steen K T Ooi; Timothy H Bestor
Journal: Cell Date: 2008-06-27 Impact factor: 41.582

Review 5. Non-B DNA structure-induced genetic instability and evolution.

Authors: Junhua Zhao; Albino Bacolla; Guliang Wang; Karen M Vasquez
Journal: Cell Mol Life Sci Date: 2009-09-01 Impact factor: 9.261

6. Reprogramming towards pluripotency requires AID-dependent DNA demethylation.

Authors: Nidhi Bhutani; Jennifer J Brady; Mara Damian; Alessandra Sacco; Stéphane Y Corbel; Helen M Blau
Journal: Nature Date: 2010-02-25 Impact factor: 49.962

Review 7. The epigenomics of cancer.

Authors: Peter A Jones; Stephen B Baylin
Journal: Cell Date: 2007-02-23 Impact factor: 41.582

Review 8. Biochemical basis of immunological and retroviral responses to DNA-targeted cytosine deamination by activation-induced cytidine deaminase and APOBEC3G.

Authors: Linda Chelico; Phuong Pham; John Petruska; Myron F Goodman
Journal: J Biol Chem Date: 2009-08-13 Impact factor: 5.157

Review 9. The biochemistry of somatic hypermutation.

Authors: Jonathan U Peled; Fei Li Kuang; Maria D Iglesias-Ussel; Sergio Roa; Susan L Kalis; Myron F Goodman; Matthew D Scharff
Journal: Annu Rev Immunol Date: 2008 Impact factor: 28.527

Review 10. Base J: discovery, biosynthesis, and possible functions.

Authors: Piet Borst; Robert Sabatini
Journal: Annu Rev Microbiol Date: 2008 Impact factor: 15.500

1 in total

Review 1. The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.

Authors: Christopher S Nabel; Sara A Manning; Rahul M Kohli
Journal: ACS Chem Biol Date: 2011-10-31 Impact factor: 5.100

1 in total