Literature DB >> 2107798

Ultraviolet radiation suppresses mouse-ear edema induced by topical application of arachidonic acid.

K Danno1, K Toda, K Ikai, T Horio, S Imamura.   

Abstract

The effect of ultraviolet (UV) radiation on arachidonic acid (AA) cascade was examined using an in vivo model. Mouse ear lobes were painted with 1 mg AA, and the maximum response of ear swelling was measured 1 h after challenge. Arachidonic-acid-induced ear swelling was significantly suppressed by preexposure to topical psoralen plus noninflammatory doses of long-wave UV radiation (PUVA) or middle-wave UV (UVB) radiation. Ultraviolet radiation may interfere with AA pathways to suppress ear swelling since AA-induced ear swelling is considered to be mediated by metabolites derived from exogenous AA. The results may relate to the therapeutic mechanisms of UV radiation in psoriasis in which the eicosanoid cascade is involved.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2107798     DOI： 10.1007/bf00505644

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  19 in total

1.  Effect of 8-methoxypsoralen plus long-wave ultraviolet (PUVA) radiation on mast cells. II. In vitro PUVA inhibits degranulation of rat peritoneal mast cells induced by compound 48/80.

Authors:  K Toda; K Danno; T Tachibana; T Horio
Journal:  J Invest Dermatol       Date:  1986-07       Impact factor: 8.551

2.  Suppressed histamine release from rat peritoneal mast cells by ultraviolet B irradiation: decreased diacylglycerol formation as a possible mechanism.

Authors:  K Danno; K Fujii; T Tachibana; K Toda; T Horio
Journal:  J Invest Dermatol       Date:  1988-06       Impact factor: 8.551

3.  The effect of combined ultraviolet A irradiation and oral psoralens (PUVA) on skin arachidonic acid and prostaglandin concentrations in psoriasis [proceedings].

Authors:  M W Greaves; C N Hensby; N A Plummer; A P Warin
Journal:  Br J Pharmacol       Date:  1978-06       Impact factor: 8.739

4.  The mouse ear inflammatory response to topical arachidonic acid.

Authors:  J M Young; D A Spires; C J Bedord; B Wagner; S J Ballaron; L M De Young
Journal:  J Invest Dermatol       Date:  1984-04       Impact factor: 8.551

5.  Changes in arachidonic acid metabolism in UV-irradiated hairless mouse skin.

Authors:  T Ruzicka; J F Walter; M P Printz
Journal:  J Invest Dermatol       Date:  1983-10       Impact factor: 8.551

6.  Ultraviolet-B radiation suppresses mast cell degranulation induced by compound 48/80.

Authors:  K Danno; K Toda; T Horio
Journal:  J Invest Dermatol       Date:  1986-12       Impact factor: 8.551

7.  Pharmacological profile of AA-861, a 5-lipoxygenase inhibitor.

Authors:  Y Ashida; T Saijo; H Kuriki; H Makino; S Terao; Y Maki
Journal:  Prostaglandins       Date:  1983-12

8.  The effect of 8-methoxypsoralen plus long-wave ultraviolet (PUVA) radiation on mast cells: PUVA suppresses degranulation of mouse skin mast cells induced by compound 48/80 or concanavalin A.

Authors:  K Danno; K Toda; T Horio
Journal:  J Invest Dermatol       Date:  1985-08       Impact factor: 8.551

9.  Time course changes in levels of arachidonic acid and prostaglandins D2, E2, F2 alpha in human skin following ultraviolet B irradiation.

Authors:  A K Black; N Fincham; M W Greaves; C N Hensby
Journal:  Br J Clin Pharmacol       Date:  1980-11       Impact factor: 4.335

10.  Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid.

Authors:  E E Opas; R J Bonney; J L Humes
Journal:  J Invest Dermatol       Date:  1985-04       Impact factor: 8.551
View more
  1 in total

1.  Anti-inflammatory effects of eicosapentaenoic acid on experimental skin inflammation models.

Authors:  K Danno; K Ikai; S Imamura
Journal:  Arch Dermatol Res       Date:  1993       Impact factor: 3.017
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.