Literature DB >> 8304784

Anti-inflammatory effects of eicosapentaenoic acid on experimental skin inflammation models.

K Danno1, K Ikai, S Imamura.   

Abstract

Anti-inflammatory effects of eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) were examined on three models of skin inflammation induced in mice by topical application of an arachidonic acid (AA) solution, ultraviolet-B (UVB) irradiation, and contact sensitization with dinitrofluorobenzene. Ear oedema reactions induced by AA and UVB irradiation were significantly suppressed in mice fed a daily dose of 300 mg/kg EPA for 2 weeks. The contact hypersensitivity reaction was not impaired by EPA. None of the skin reactions was significantly inhibited in mice fed DHA or safflower oil. The results suggest that EPA, but not DHA, has anti-inflammatory effects on AA- and UVB-induced acute inflammation reactions.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8304784     DOI： 10.1007/BF00372139

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  23 in total

1.  The effects of dietary supplementation with fish oil in patients with psoriasis.

Authors:  P D Maurice; B R Allen; A S Barkley; S R Cockbill; J Stammers; P C Bather
Journal:  Br J Dermatol       Date:  1987-11       Impact factor: 9.302

2.  Effects of dietary supplementation of fish oil on neutrophil and epidermal fatty acids. Modulation of clinical course of psoriatic subjects.

Authors:  V A Ziboh; K A Cohen; C N Ellis; C Miller; T A Hamilton; K Kragballe; C R Hydrick; J J Voorhees
Journal:  Arch Dermatol       Date:  1986-11

3.  Eicosapentaenoic acid as a modulator of inflammation. Effect on prostaglandin and leukotriene synthesis.

Authors:  T Terano; J A Salmon; G A Higgs; S Moncada
Journal:  Biochem Pharmacol       Date:  1986-03-01       Impact factor: 5.858

4.  Biosynthesis and biological activity of leukotriene B5.

Authors:  T Terano; J A Salmon; S Moncada
Journal:  Prostaglandins       Date:  1984-02

5.  Long-term administration of highly purified eicosapentaenoic acid provides improvement of psoriasis.

Authors:  T Kojima; T Terano; E Tanabe; S Okamoto; Y Tamura; S Yoshida
Journal:  Dermatologica       Date:  1991

6.  Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.

Authors:  T H Lee; J M Mencia-Huerta; C Shih; E J Corey; R A Lewis; K F Austen
Journal:  J Clin Invest       Date:  1984-12       Impact factor: 14.808

7.  Time course changes in levels of arachidonic acid and prostaglandins D2, E2, F2 alpha in human skin following ultraviolet B irradiation.

Authors:  A K Black; N Fincham; M W Greaves; C N Hensby
Journal:  Br J Clin Pharmacol       Date:  1980-11       Impact factor: 4.335

8.  Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid.

Authors:  E E Opas; R J Bonney; J L Humes
Journal:  J Invest Dermatol       Date:  1985-04       Impact factor: 8.551

9.  Effect of eicosapentaenoic and docosahexaenoic acid on natural killer cell activity in human peripheral blood lymphocytes.

Authors:  N Yamashita; M Maruyama; K Yamazaki; T Hamazaki; S Yano
Journal:  Clin Immunol Immunopathol       Date:  1991-06

10.  A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice.

Authors:  V E Kelley; A Ferretti; S Izui; T B Strom
Journal:  J Immunol       Date:  1985-03       Impact factor: 5.422
View more
  4 in total

1.  Dietary docosahexaenoic acid suppresses inflammation and immunoresponses in contact hypersensitivity reaction in mice.

Authors:  Y I Tomobe; K Morizawa; M Tsuchida; H Hibino; Y Nakano; Y Tanaka
Journal:  Lipids       Date:  2000-01       Impact factor: 1.880

2.  Fermented fish oil suppresses T helper 1/2 cell response in a mouse model of atopic dermatitis via generation of CD4+CD25+Foxp3+ T cells.

Authors:  Sang-Chul Han; Gyeoung-Jin Kang; Yeong-Jong Ko; Hee-Kyoung Kang; Sang-Wook Moon; Yong-Seok Ann; Eun-Sook Yoo
Journal:  BMC Immunol       Date:  2012-08-09       Impact factor: 3.615

Review 3.  Cosmetic and Therapeutic Applications of Fish Oil's Fatty Acids on the Skin.

Authors:  Tse-Hung Huang; Pei-Wen Wang; Shih-Chun Yang; Wei-Ling Chou; Jia-You Fang
Journal:  Mar Drugs       Date:  2018-07-30       Impact factor: 5.118

4.  Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators.

Authors:  Yoshimi Miki; Kei Yamamoto; Yoshitaka Taketomi; Hiroyasu Sato; Kanako Shimo; Tetsuyuki Kobayashi; Yukio Ishikawa; Toshiharu Ishii; Hiroki Nakanishi; Kazutaka Ikeda; Ryo Taguchi; Kenji Kabashima; Makoto Arita; Hiroyuki Arai; Gérard Lambeau; James M Bollinger; Shuntaro Hara; Michael H Gelb; Makoto Murakami
Journal:  J Exp Med       Date:  2013-05-20       Impact factor: 14.307
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.