Literature DB >> 21071927

Health system implications of direct-to-consumer personal genome testing.

Amy L McGuire1, Wylie Burke.   

Abstract

Direct-to-consumer personal genome testing is now widely available to consumers. Proponents argue that knowledge is power but critics worry about consumer safety and potential harms resulting from misinterpretation of test information. In this article, we consider the health system implications of direct-to-consumer personal genome testing, focusing on issues of accountability, both corporate and professional.
Copyright © 2010 S. Karger AG, Basel.

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Year:  2010        PMID: 21071927      PMCID: PMC3025885          DOI: 10.1159/000321962

Source DB:  PubMed          Journal:  Public Health Genomics        ISSN: 1662-4246            Impact factor:   2.000


  18 in total

1.  A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions.

Authors:  A Cecile J W Janssens; Marta Gwinn; Linda A Bradley; Ben A Oostra; Cornelia M van Duijn; Muin J Khoury
Journal:  Am J Hum Genet       Date:  2008-03       Impact factor: 11.025

2.  Letting the genome out of the bottle--will we get our wish?

Authors:  David J Hunter; Muin J Khoury; Jeffrey M Drazen
Journal:  N Engl J Med       Date:  2008-01-10       Impact factor: 91.245

3.  Currents in contemporary ethics. Direct-to-consumer genetic testing: is it the practice of medicine?

Authors:  Cynthia Marietta; Amy L McGuire
Journal:  J Law Med Ethics       Date:  2009       Impact factor: 1.718

4.  Reforming health care or reforming health?

Authors:  Thomas A Farley
Journal:  Am J Public Health       Date:  2009-02-05       Impact factor: 9.308

5.  Personal genomes: Misdirected precaution.

Authors:  Barbara Prainsack; Jenny Reardon; Richard Hindmarsh; Herbert Gottweis; Ursula Naue; Jeantine E Lunshof
Journal:  Nature       Date:  2008-11-06       Impact factor: 49.962

Review 6.  The current landscape for direct-to-consumer genetic testing: legal, ethical, and policy issues.

Authors:  Stuart Hogarth; Gail Javitt; David Melzer
Journal:  Annu Rev Genomics Hum Genet       Date:  2008       Impact factor: 8.929

Review 7.  Cascade effects of medical technology.

Authors:  Richard A Deyo
Journal:  Annu Rev Public Health       Date:  2001-10-25       Impact factor: 21.981

Review 8.  Comparative effectiveness research and genomic medicine: an evolving partnership for 21st century medicine.

Authors:  Muin J Khoury; Eugene C Rich; Gurvaneet Randhawa; Steven M Teutsch; John Niederhuber
Journal:  Genet Med       Date:  2009-10       Impact factor: 8.822

9.  The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop.

Authors:  Muin J Khoury; Colleen M McBride; Sheri D Schully; John P A Ioannidis; W Gregory Feero; A Cecile J W Janssens; Marta Gwinn; Denise G Simons-Morton; Jay M Bernhardt; Michele Cargill; Stephen J Chanock; George M Church; Ralph J Coates; Francis S Collins; Robert T Croyle; Barry R Davis; Gregory J Downing; Amy Duross; Susan Friedman; Mitchell H Gail; Geoffrey S Ginsburg; Robert C Green; Mark H Greene; Philip Greenland; Jeffrey R Gulcher; Andro Hsu; Kathy L Hudson; Sharon L R Kardia; Paul L Kimmel; Michael S Lauer; Amy M Miller; Kenneth Offit; David F Ransohoff; J Scott Roberts; Rebekah S Rasooly; Kari Stefansson; Sharon F Terry; Steven M Teutsch; Angela Trepanier; Kay L Wanke; John S Witte; Jianfeng Xu
Journal:  Genet Med       Date:  2009-08       Impact factor: 8.822

10.  Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors.

Authors: 
Journal:  Genet Med       Date:  2007-12       Impact factor: 8.822

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  13 in total

1.  Neither as harmful as feared by critics nor as empowering as promised by providers: risk information offered direct to consumer by personal genomics companies.

Authors:  Anders Nordgren
Journal:  J Community Genet       Date:  2012-04-05

2.  Risky business: risk perception and the use of medical services among customers of DTC personal genetic testing.

Authors:  David J Kaufman; Juli M Bollinger; Rachel L Dvoskin; Joan A Scott
Journal:  J Genet Couns       Date:  2012-01-26       Impact factor: 2.537

Review 3.  Direct-to-consumer personalized genomic testing.

Authors:  Cinnamon S Bloss; Burcu F Darst; Eric J Topol; Nicholas J Schork
Journal:  Hum Mol Genet       Date:  2011-08-09       Impact factor: 6.150

4.  Primary care patients' views and decisions about, experience of and reactions to direct-to-consumer genetic testing: a longitudinal study.

Authors:  Katherine Wasson; Tonya Nashay Sanders; Nancy S Hogan; Sara Cherny; Kathy J Helzlsouer
Journal:  J Community Genet       Date:  2013-07-07

Review 5.  Evolving approaches to the ethical management of genomic data.

Authors:  Jean E McEwen; Joy T Boyer; Kathie Y Sun
Journal:  Trends Genet       Date:  2013-02-28       Impact factor: 11.639

Review 6.  Implementing genomics and pharmacogenomics in the clinic: The National Human Genome Research Institute's genomic medicine portfolio.

Authors:  Teri A Manolio
Journal:  Atherosclerosis       Date:  2016-08-26       Impact factor: 5.162

7.  Increasing Public Awareness of Direct-to-Consumer Genetic Tests: Health Care Access, Internet Use, and Population Density Correlates.

Authors:  Lila J Finney Rutten; Sarah E Gollust; Sana Naveed; Richard P Moser
Journal:  J Cancer Epidemiol       Date:  2012-07-30

8.  Health care providers and direct-to-consumer access and advertising of genetic testing in the United States.

Authors:  Melanie F Myers
Journal:  Genome Med       Date:  2011-12-28       Impact factor: 15.266

9.  Attitudes towards Social Networking and Sharing Behaviors among Consumers of Direct-to-Consumer Personal Genomics.

Authors:  Sandra Soo-Jin Lee; Simone L Vernez; K E Ormond; Mark Granovetter
Journal:  J Pers Med       Date:  2013-10-14

Review 10.  Values in translation: how asking the right questions can move translational science toward greater health impact.

Authors:  Maureen Kelley; Kelly Edwards; Helene Starks; Stephanie M Fullerton; Rosalina James; Sara Goering; Suzanne Holland; Mary L Disis; Wylie Burke
Journal:  Clin Transl Sci       Date:  2012-08-07       Impact factor: 4.689

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