Literature DB >> 21060917

Cu K-edge X-ray absorption spectroscopy reveals differential copper coordination within amyloid-β oligomers compared to amyloid-β monomers.

Jason Shearer1, Paige E Callan, Thao Tran, Veronika A Szalai.   

Abstract

The fatal neurological disorder Alzheimer's disease has been linked to soluble neurotoxic oligomers of amyloid-β (Aβ) peptides. Herein we demonstrate that Cu(1+) ligated within Aβ(42) oligomers (Aβ sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA) possesses a highly dioxygen sensitive tetrahedral coordination geometry. The biological implications of these findings are discussed.

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Year:  2010        PMID： 21060917      PMCID： PMC3082590          DOI： 10.1039/c0cc02446e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  13 in total

1.  Affinity of Cu+ for the copper-binding domain of the amyloid-β peptide of Alzheimer's disease.

Authors:  Heather A Feaga; Richard C Maduka; Monique N Foster; Veronika A Szalai
Journal:  Inorg Chem       Date:  2011-01-31       Impact factor: 5.165

2.  Global prevalence of dementia: a Delphi consensus study.

Authors:  Cleusa P Ferri; Martin Prince; Carol Brayne; Henry Brodaty; Laura Fratiglioni; Mary Ganguli; Kathleen Hall; Kazuo Hasegawa; Hugh Hendrie; Yueqin Huang; Anthony Jorm; Colin Mathers; Paulo R Menezes; Elizabeth Rimmer; Marcia Scazufca
Journal:  Lancet       Date:  2005-12-17       Impact factor: 79.321

3.  Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease.

Authors:  Stefan Barghorn; Volker Nimmrich; Andreas Striebinger; Carsten Krantz; Patrick Keller; Bodo Janson; Michael Bahr; Martin Schmidt; Robert S Bitner; John Harlan; Eve Barlow; Ulrich Ebert; Heinz Hillen
Journal:  J Neurochem       Date:  2005-08-31       Impact factor: 5.372

4.  N-Terminal deletions modify the Cu2+ binding site in amyloid-beta.

Authors:  Jesse W Karr; Henrietta Akintoye; Lauren J Kaupp; Veronika A Szalai
Journal:  Biochemistry       Date:  2005-04-12       Impact factor: 3.162

5.  Metal binding in amyloid beta-peptides shows intra- and inter-peptide coordination modes.

Authors:  Francesco Stellato; Gianfranco Menestrina; Mauro Dalla Serra; Cristina Potrich; Rossella Tomazzolli; Wolfram Meyer-Klaucke; Silvia Morante
Journal:  Eur Biophys J       Date:  2006-01-11       Impact factor: 1.733

6.  Structure-neurotoxicity relationships of amyloid beta-protein oligomers.

Authors:  Kenjiro Ono; Margaret M Condron; David B Teplow
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-12       Impact factor: 11.205

Review 7.  Copper in the brain and Alzheimer's disease.

Authors:  Ya Hui Hung; Ashley I Bush; Robert Alan Cherny
Journal:  J Biol Inorg Chem       Date:  2009-10-28       Impact factor: 3.358

8.  The amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptide.

Authors:  Jason Shearer; Veronika A Szalai
Journal:  J Am Chem Soc       Date:  2008-12-31       Impact factor: 15.419

9.  Coordination abilities of the 1-16 and 1-28 fragments of beta-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study.

Authors:  Teresa Kowalik-Jankowska; Monika Ruta; Kornelia Wiśniewska; Leszek Lankiewicz
Journal:  J Inorg Biochem       Date:  2003-07-01       Impact factor: 4.155

10.  A presenilin 1 mutation (Arg278Ser) associated with early onset Alzheimer's disease and spastic paraparesis.

Authors:  Ashok Raman; Xia Lin; Mohnish Suri; Monica Hewitt; Cris S Constantinescu; Margaret F Phillips
Journal:  J Neurol Sci       Date:  2007-05-15       Impact factor: 3.181
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  11 in total

1.  The elevated copper binding strength of amyloid-β aggregates allows the sequestration of copper from albumin: a pathway to accumulation of copper in senile plaques.

Authors:  Dianlu Jiang; Lin Zhang; Gian Paola G Grant; Christopher G Dudzik; Shu Chen; Sveti Patel; Yuanqiang Hao; Glenn L Millhauser; Feimeng Zhou
Journal:  Biochemistry       Date:  2013-01-11       Impact factor: 3.162

2.  Aggregation pathways of the amyloid β(1-42) peptide depend on its colloidal stability and ordered β-sheet stacking.

Authors:  Dianlu Jiang; Iris Rauda; Shubo Han; Shu Chen; Feimeng Zhou
Journal:  Langmuir       Date:  2012-08-22       Impact factor: 3.882

3.  Exploring the reactivity of flavonoid compounds with metal-associated amyloid-β species.

Authors:  Xiaoming He; Hyun Min Park; Suk-Joon Hyung; Alaina S DeToma; Cheal Kim; Brandon T Ruotolo; Mi Hee Lim
Journal:  Dalton Trans       Date:  2012-03-22       Impact factor: 4.390

4.  Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β Species.

Authors:  Alaina S DeToma; Janarthanan Krishnamoorthy; Younwoo Nam; Hyuck Jin Lee; Jeffrey R Brender; Akiko Kochi; Dongkuk Lee; Valentina Onnis; Cenzo Congiu; Stefano Manfredini; Silvia Vertuani; Gianfranco Balboni; Ayyalusamy Ramamoorthy; Mi Hee Lim
Journal:  Chem Sci       Date:  2014-12-01       Impact factor: 9.825

5.  Amyloid-beta-copper interaction studied by simultaneous nitrogen K and copper L2,3 -edge soft X-ray absorption spectroscopy.

Authors:  Jinghui Luo; Hongzhi Wang; Jinming Wu; Vladyslav Romankov; Niéli Daffé; Jan Dreiser
Journal:  iScience       Date:  2021-11-16

6.  Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid β-fibrils in a redox cycle.

Authors:  Sudhakar Parthasarathy; Brian Yoo; Dan McElheny; William Tay; Yoshitaka Ishii
Journal:  J Biol Chem       Date:  2014-02-12       Impact factor: 5.157

7.  Local structure and global patterning of Cu2+ binding in fibrillar amyloid-β [Aβ(1-40)] protein.

Authors:  William A Gunderson; Jessica Hernández-Guzmán; Jesse W Karr; Li Sun; Veronika A Szalai; Kurt Warncke
Journal:  J Am Chem Soc       Date:  2012-10-24       Impact factor: 15.419

8.  Copper ligation to soluble oligomers of the English mutant of the amyloid-β peptide yields a linear Cu(I) site that is resistant to O2 oxidation.

Authors:  Kristy L Peck; Heather S Clewett; Jennifer C Schmitt; Jason Shearer
Journal:  Chem Commun (Camb)       Date:  2013-05-25       Impact factor: 6.222

Review 9.  Curcumin in Health and Diseases: Alzheimer's Disease and Curcumin Analogues, Derivatives, and Hybrids.

Authors:  Eirini Chainoglou; Dimitra Hadjipavlou-Litina
Journal:  Int J Mol Sci       Date:  2020-03-13       Impact factor: 5.923

10.  Tuning and Probing the Distribution of Cu+ and Cu2+ Trap States Responsible for Broad-Band Photoluminescence in CuInS2 Nanocrystals.

Authors:  Ward van der Stam; Max de Graaf; Solrun Gudjonsdottir; Jaco J Geuchies; Jurgen J Dijkema; Nicholas Kirkwood; Wiel H Evers; Alessandro Longo; Arjan J Houtepen
Journal:  ACS Nano       Date:  2018-10-31       Impact factor: 15.881
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