| Literature DB >> 21057373 |
Maaike A Kusters1, C M Jol-van der Zijde, Maarten J van Tol, W E Bolz, L A Bok, Marjan Visser, Esther de Vries.
Abstract
Down syndrome children show a decreased avidity of the antibody response after tetanus toxoid booster vaccination at 9 years of age suggesting impaired memory B cell selection in the germinal center. Clinicians need to be aware of this ongoing subtle immunologic deficit in Down syndrome.Entities:
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Year: 2011 PMID: 21057373 DOI: 10.1097/INF.0b013e3181ff85a8
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN: 0891-3668 Impact factor: 2.129