Literature DB >> 2105151

Hip fractures in young patients: is this early osteoporosis?

S D Boden1, P Labropoulos, R Saunders.   

Abstract

Hip fracture in patients under age 50 is rare, and is often not attributable solely to the energy of injury. Our aim was to determine if trabecular bone mineral density (BMD) is abnormal in young patients with hip fractures. We reviewed all hip fractures treated at our institution between 1979 and 1986 and contacted 20 patients under the age of 50 at the time of injury, all of whom wished to be studied. The mean age at the time of injury was 39 (range 24-47). Subjects were questioned for osteoporosis risk factors, classified by level of energy producing their injury, and then underwent quantitative computed tomography (QCT) bone densitometry of trabecular bone in the lumbar spine. Bone mineral density by QCT was below the mean for age in 90% of the patients, and was greater than 1 SD below the mean in 75%. Mean percentage BMD decrease from age-matched controls was 34% (P less than 0.005) in women and 19% (P less than 0.005) in men. There was an inverse correlation in the degree of BMD decrease and the energy level of injury. There was a direct correlation of the severity of BMD decrease and the cumulative number of osteoporosis risk factors. This investigation has found that 1-7 years following hip fracture, otherwise presumedly healthy young patients demonstrate a statistically significant decrease in spinal BMD from age/sex-matched controls. These data do not determine if osteopenia is the cause or the result of injury, nor do we wish to infer that measurement of bone density at one site can predict future fractures at other sites.(ABSTRACT TRUNCATED AT 250 WORDS)

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Year:  1990        PMID: 2105151     DOI: 10.1007/bf02556089

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN: 0171-967X            Impact factor:   4.333


  51 in total

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Journal:  Lancet       Date:  1979-07-21       Impact factor: 79.321

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Authors:  C E Cann; H K Genant; D R Young
Journal:  Radiology       Date:  1980-02       Impact factor: 11.105

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Journal:  Invest Radiol       Date:  1985 May-Jun       Impact factor: 6.016

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Journal:  J Bone Joint Surg Am       Date:  1979-10       Impact factor: 5.284

10.  Effect of weight, smoking, and estrogen use on the risk of hip and forearm fractures in postmenopausal women.

Authors:  A R Williams; N S Weiss; C L Ure; J Ballard; J R Daling
Journal:  Obstet Gynecol       Date:  1982-12       Impact factor: 7.661

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  9 in total

1.  Young patients with hip fracture: a population-based study of bone mass and risk factors for osteoporosis.

Authors:  C M Lofthus; E K Osnes; H E Meyer; I S Kristiansen; L Nordsletten; J A Falch
Journal:  Osteoporos Int       Date:  2006-08-29       Impact factor: 4.507

2.  Does back pain predict subsequent fracture in postmenopausal women?

Authors:  K Nakamura; M R Sowers
Journal:  Environ Health Prev Med       Date:  1997-01       Impact factor: 3.674

Review 3.  Management of femoral neck fractures in the young patient: A critical analysis review.

Authors:  Thierry Pauyo; Justin Drager; Anthony Albers; Edward J Harvey
Journal:  World J Orthop       Date:  2014-07-18

4.  Low bone mineral density, grip strength and skinfold thickness are important risk factors for hip fracture in Hong Kong Chinese.

Authors:  E M Lau; J Woo; P C Leung; R Swaminthan
Journal:  Osteoporos Int       Date:  1993-03       Impact factor: 4.507

5.  Clinical Risk Factors for Hip Fracture in Young Adults Under 50 Years Old.

Authors:  Kenneth Cheng; Sandy Montgomery; Sarah Housley; Eugene Wheelwright
Journal:  Eur J Trauma Emerg Surg       Date:  2008-07-22       Impact factor: 3.693

6.  [Radius fractures in typical sites in young patients--is it early osteoporosis?].

Authors:  G Oberthaler; H Kässmann; J Holzmannhofer; C Primavesi
Journal:  Unfallchirurgie       Date:  1995-06

7.  Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study.

Authors:  Tsai-Hsueh Leu; Wei-Chun Chang; Jeff Chien-Fu Lin; Chi Lo; Wen-Miin Liang; Yu-Jun Chang; Dann-Pyng Shih; Cheng-Chun Wu; Chi-Fung Cheng; Sy-Jye Wei
Journal:  BMC Musculoskelet Disord       Date:  2016-08-05       Impact factor: 2.362

8.  Frailty and osteoporosis in patients with hip fractures under the age of 60-a prospective cohort of 218 individuals.

Authors:  Sebastian Strøm Rönnquist; Bjarke Viberg; Morten Tange Kristensen; Henrik Palm; Jens-Erik Beck Jensen; Carsten Fladmose Madsen; Kristina E Åkesson; Søren Overgaard; Cecilia Rogmark
Journal:  Osteoporos Int       Date:  2022-01-14       Impact factor: 4.507

9.  Risk factors for osteoporosis are common in young and middle-aged patients with femoral neck fractures regardless of trauma mechanism.

Authors:  Amer N Al-Ani; Gustaf Neander; Bodil Samuelsson; Richard Blomfeldt; Wilhelmina Ekström; Margareta Hedström
Journal:  Acta Orthop       Date:  2013-01-23       Impact factor: 3.717

  9 in total

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