BACKGROUND: Intrauterine growth restriction (IUGR) is associated with several medical complications before and after delivery. The aim of this study was to evaluate the concordance between the fetal ultrasonographic measurement of subcutaneous tissue thicknesses and the skinfold thicknesses assessment in intrauterine growth restricted newborns. METHODS: We designed an exploratory study. Fetal ultrasonographic measurement of subcutaneous tissue thicknesses, according to Bernstein's and Galan's method, and neonatal skinfold thicknesses were evaluated in 13 intrauterine growth restricted newborns within 4 hours before delivery and on the first day of life, respectively. Concordance between fetal and neonatal measurements was assessed using the Lin's correlation coefficient and the Bland-Altman method. RESULTS: The data obtained by the measurements of neonatal skinfold thicknesses was significantly correlated with the prenatal measurements (Lin's coefficients, arm: 0.60; subscapular: 0.72; abdomen: 0.51). Bland-Altman analysis showed moderate agreement between the fetal ultrasonographic measurement of subcutaneous tissue thicknesses and the neonatal skinfold thicknesses assessment. CONCLUSIONS: The present study provides preliminary evidence that fetal sonographic measurements may represent additional indices of intrauterine growth restriction.
BACKGROUND: Intrauterine growth restriction (IUGR) is associated with several medical complications before and after delivery. The aim of this study was to evaluate the concordance between the fetal ultrasonographic measurement of subcutaneous tissue thicknesses and the skinfold thicknesses assessment in intrauterine growth restricted newborns. METHODS: We designed an exploratory study. Fetal ultrasonographic measurement of subcutaneous tissue thicknesses, according to Bernstein's and Galan's method, and neonatal skinfold thicknesses were evaluated in 13 intrauterine growth restricted newborns within 4 hours before delivery and on the first day of life, respectively. Concordance between fetal and neonatal measurements was assessed using the Lin's correlation coefficient and the Bland-Altman method. RESULTS: The data obtained by the measurements of neonatal skinfold thicknesses was significantly correlated with the prenatal measurements (Lin's coefficients, arm: 0.60; subscapular: 0.72; abdomen: 0.51). Bland-Altman analysis showed moderate agreement between the fetal ultrasonographic measurement of subcutaneous tissue thicknesses and the neonatal skinfold thicknesses assessment. CONCLUSIONS: The present study provides preliminary evidence that fetal sonographic measurements may represent additional indices of intrauterine growth restriction.
Authors: H L Galan; S Rigano; T Radaelli; I Cetin; M Bozzo; J Chyu; J C Hobbins; E Ferrazzi Journal: Am J Obstet Gynecol Date: 2001-10 Impact factor: 8.661
Authors: Alessandra Padoan; Serena Rigano; Enrico Ferrazzi; Brenda L Beaty; Frederick C Battaglia; Henry L Galan Journal: Am J Obstet Gynecol Date: 2004-10 Impact factor: 8.661
Authors: T Todros; E Ferrazzi; C Groli; U Nicolini; L Parodi; M Pavoni; A Zorzoli; S Zucca Journal: J Clin Ultrasound Date: 1987-02 Impact factor: 0.910
Authors: W Lee; M Balasubramaniam; R L Deter; S S Hassan; F Gotsch; J P Kusanovic; L F Gonçalves; R Romero Journal: Ultrasound Obstet Gynecol Date: 2009-04 Impact factor: 7.299