Literature DB >> 20976035

Qualitative and quantitative analysis of retinol, retinyl esters, tocopherols and selected carotenoids out of various internal organs form different species by HPLC.

Michael W Schäffer1, Somdutta Sinha Roy, Shyamali Mukherjee, Donatus Nohr, Michael Wolter, Hans K Biesalski, David E Ong, Salil K Das.   

Abstract

We report the validation of a reversed-phase gradient HPLC method allowing simultaneous quantification of retinol, retinyl esters, tocopherols and selected carotenoids in lung, liver and plasma of mouse, rat and guinea pig (gp) using a diode array detector. A significant species difference was observed regarding the distribution of retinol and retinyl esters. The levels of total retinol in lung, liver and plasma were in the following order: mouse >> rat > gp; rat >mouse > gp; and gp >> rat > mouse, respectively. Furthermore, comparison studies revealed similarities between the vitamin A profiles of human and gp lung samples.

Entities:  

Year:  2010        PMID： 20976035      PMCID： PMC2957904          DOI： 10.1039/c0ay00288g

Source DB:  PubMed          Journal:  Anal Methods        ISSN： 1759-9660            Impact factor:   2.896


  35 in total

1.  Alterations in binding characteristics of peripheral benzodiazepine receptors in testes by vitamin A deficiency in guinea pigs.

Authors:  T Nayyar; S Mukherjee; S K Das
Journal:  Mol Cell Biochem       Date:  2000-08       Impact factor: 3.396

2.  HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues.

Authors:  Maureen A Kane; Alexandra E Folias; Joseph L Napoli
Journal:  Anal Biochem       Date:  2008-03-25       Impact factor: 3.365

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Journal:  Arch Biochem Biophys       Date:  1984-04       Impact factor: 4.013

5.  9-cis-retinoids: biosynthesis of 9-cis-retinoic acid.

Authors:  J Paik; S Vogel; R Piantedosi; A Sykes; W S Blaner; K Swisshelm
Journal:  Biochemistry       Date:  2000-07-11       Impact factor: 3.162

6.  Depletion of retinyl esters in the lungs coincides with lung prenatal morphological maturation.

Authors:  S K Geevarghese; F Chytil
Journal:  Biochem Biophys Res Commun       Date:  1994-04-15       Impact factor: 3.575

7.  Rapid analysis of the major classes of retinoids by step gradient reversed-phase high-performance liquid chromatography using retinal (O-ethyl) oxime derivatives.

Authors:  F J van Kuijk; G J Handelman; E A Dratz
Journal:  J Chromatogr       Date:  1985-11-27

Review 8.  Regulation of hepatic retinol metabolism: perspectives from studies on vitamin A status.

Authors:  A Catharine Ross; Reza Zolfaghari
Journal:  J Nutr       Date:  2004-01       Impact factor: 4.798

9.  9-cis retinoic acid is a high affinity ligand for the retinoid X receptor.

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Journal:  Cell       Date:  1992-01-24       Impact factor: 41.582

10.  Impact of neonatal vitamin A supplementation on infant morbidity and mortality.

Authors:  J H Humphrey; T Agoestina; L Wu; A Usman; M Nurachim; D Subardja; S Hidayat; J Tielsch; K P West; A Sommer
Journal:  J Pediatr       Date:  1996-04       Impact factor: 4.406
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  6 in total

1.  Uptake of all-trans retinoic acid-containing aerosol by inhalation to lungs in a guinea pig model system--a pilot study.

Authors:  Michael W Schäffer; Somdutta Sinha Roy; Shyamali Mukherjee; David E Ong; Salil K Das
Journal:  Exp Lung Res       Date:  2010-12       Impact factor: 2.459

2.  Interspecies comparison of stellate cell-containing macula flavae and vitamin A storage in vocal fold mucosa.

Authors:  Yutaka Toya; Napaporn Riabroy; Christopher R Davis; Yo Kishimoto; Sherry A Tanumihardjo; Diane M Bless; Nathan V Welham
Journal:  J Anat       Date:  2014-07-04       Impact factor: 2.610

3.  Intravital microscopy of biosensor activities and intrinsic metabolic states.

Authors:  Seth Winfree; Takashi Hato; Richard N Day
Journal:  Methods       Date:  2017-04-21       Impact factor: 3.608

4.  Vitamin A supplementation alleviates extrahepatic cholestasis liver injury through Nrf2 activation.

Authors:  Guiyang Wang; Peng Xiu; Fu Li; Cheng Xin; Kewei Li
Journal:  Oxid Med Cell Longev       Date:  2014-07-09       Impact factor: 6.543

5.  Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes.

Authors:  Ali Saeed; Paulina Bartuzi; Janette Heegsma; Daphne Dekker; Niels Kloosterhuis; Alain de Bruin; Johan W Jonker; Bart van de Sluis; Klaas Nico Faber
Journal:  Cell Mol Gastroenterol Hepatol       Date:  2020-07-19

6.  ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6.

Authors:  Thomas O Eichmann; Lukas Grumet; Ulrike Taschler; Jürgen Hartler; Christoph Heier; Aaron Woblistin; Laura Pajed; Manfred Kollroser; Gerald Rechberger; Gerhard G Thallinger; Rudolf Zechner; Günter Haemmerle; Robert Zimmermann; Achim Lass
Journal:  J Lipid Res       Date:  2015-08-31       Impact factor: 5.922
  6 in total

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