Literature DB >> 8166727

Depletion of retinyl esters in the lungs coincides with lung prenatal morphological maturation.

S K Geevarghese1, F Chytil.   

Abstract

Close to birth rat fetuses have lungs which are depleted in retinyl esters. Glucocorticoids administered to pregnant rats accelerate this process. We have investigated changes in fetal lung levels of retinol and retinyl palmitate and accompanying morphological changes after administration of dexamethasone to pregnant rats on day 18 of pregnancy. Here we show that this depletion temporarily coincides with prenatal morphological maturation of the lungs. The data presented support the idea that the maturational effect of glucocorticoids in the developing lungs is linked to vitamin A metabolism.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8166727     DOI： 10.1006/bbrc.1994.1480

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

1.  Qualitative and quantitative analysis of retinol, retinyl esters, tocopherols and selected carotenoids out of various internal organs form different species by HPLC.

Authors:  Michael W Schäffer; Somdutta Sinha Roy; Shyamali Mukherjee; Donatus Nohr; Michael Wolter; Hans K Biesalski; David E Ong; Salil K Das
Journal:  Anal Methods       Date:  2010       Impact factor: 2.896

2.  Retinoic acid promotes tissue vitamin A status and modulates adipose tissue metabolism of neonatal rats exposed to maternal high-fat diet-induced obesity.

Authors:  Libo Tan; Yanqi Zhang; Hui Wang; Heleena Haberer
Journal:  J Nutr Sci       Date:  2022-07-08

3.  Vitamin A concentrations in piglet extrahepatic tissues respond differently ten days after vitamin A treatment.

Authors:  Ting Sun; Rebecca L Surles; Sherry A Tanumihardjo
Journal:  J Nutr       Date:  2008-06       Impact factor: 4.798

Review 4.  Retinoic acid in alveolar development, maintenance and regeneration.

Authors:  Malcolm Maden; Matthew Hind
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-05-29       Impact factor: 6.237

5.  Retinol kinetics in unsupplemented and vitamin A-retinoic acid supplemented neonatal rats: a preliminary model.

Authors:  Libo Tan; Amanda E Wray; Michael H Green; A Catharine Ross
Journal:  J Lipid Res       Date:  2014-04-07       Impact factor: 5.922

6.  Acidic retinoids in small amounts promote retinyl ester formation in neonatal lung, with transient increases in retinoid homeostatic gene expression.

Authors:  Lili Wu; Reza Zolfaghari; A Catharine Ross
Journal:  Nutr Metab (Lond)       Date:  2013-12-19       Impact factor: 4.169

7.  Inhibition of pulmonary β-carotene 15, 15'-oxygenase expression by glucocorticoid involves PPARα.

Authors:  Xiaoming Gong; Raju Marisiddaiah; Lewis P Rubin
Journal:  PLoS One       Date:  2017-07-21       Impact factor: 3.240

8.  Vitamin A Status and Deposition in Neonatal and Weanling Rats Reared by Mothers Consuming Normal and High-Fat Diets with Adequate or Supplemented Vitamin A.

Authors:  Yanqi Zhang; Kristi M Crowe-White; Lingyan Kong; Libo Tan
Journal:  Nutrients       Date:  2020-05-18       Impact factor: 5.717

Review 9.  Perinatal Undernutrition, Metabolic Hormones, and Lung Development.

Authors:  Juan Fandiño; Laura Toba; Lucas C González-Matías; Yolanda Diz-Chaves; Federico Mallo
Journal:  Nutrients       Date:  2019-11-23       Impact factor: 5.717

10.  Retinol and retinyl palmitate in foetal lung mice: sexual dimorphism.

Authors:  Olga Carvalho; Carlos Gonçalves
Journal:  Crit Care Res Pract       Date:  2013-01-13
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.