Literature DB >> 20966215

Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis.

Yvonne S Eisele1, Ulrike Obermüller, Götz Heilbronner, Frank Baumann, Stephan A Kaeser, Hartwig Wolburg, Lary C Walker, Matthias Staufenbiel, Mathias Heikenwalder, Mathias Jucker.   

Abstract

The intracerebral injection of β-amyloid-containing brain extracts can induce cerebral β-amyloidosis and associated pathologies in susceptible hosts. We found that intraperitoneal inoculation with β-amyloid-rich extracts induced β-amyloidosis in the brains of β-amyloid precursor protein transgenic mice after prolonged incubation times.

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Year:  2010        PMID： 20966215      PMCID： PMC3233904          DOI： 10.1126/science.1194516

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

Review 1.  The transcellular spread of cytosolic amyloids, prions, and prionoids.

Authors:  Adriano Aguzzi; Lawrence Rajendran
Journal:  Neuron       Date:  2009-12-24       Impact factor: 17.173

2.  Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid.

Authors:  M E Calhoun; P Burgermeister; A L Phinney; M Stalder; M Tolnay; K H Wiederhold; D Abramowski; C Sturchler-Pierrat; B Sommer; M Staufenbiel; M Jucker
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-23       Impact factor: 11.205

3.  Chronic lymphocytic inflammation specifies the organ tropism of prions.

Authors:  Mathias Heikenwalder; Nicolas Zeller; Harald Seeger; Marco Prinz; Peter-Christian Klöhn; Petra Schwarz; Nancy H Ruddle; Charles Weissmann; Adriano Aguzzi
Journal:  Science       Date:  2005-01-20       Impact factor: 47.728

Review 4.  The cerebral beta-amyloid angiopathies: hereditary and sporadic.

Authors:  Sandy X Zhang-Nunes; Marion L C Maat-Schieman; Sjoerd G van Duinen; Raymund A C Roos; Matthew P Frosch; Steven M Greenberg
Journal:  Brain Pathol       Date:  2006-01       Impact factor: 6.508

5.  Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: cognitive decline associated with Abeta deposition.

Authors:  Martha Storandt; Mark A Mintun; Denise Head; John C Morris
Journal:  Arch Neurol       Date:  2009-12

6.  Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease.

Authors:  John C Morris; Catherine M Roe; Elizabeth A Grant; Denise Head; Martha Storandt; Alison M Goate; Anne M Fagan; David M Holtzman; Mark A Mintun
Journal:  Arch Neurol       Date:  2009-12

7.  Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation.

Authors:  Yvonne S Eisele; Tristan Bolmont; Mathias Heikenwalder; Franziska Langer; Laura H Jacobson; Zheng-Xin Yan; Klaus Roth; Adriano Aguzzi; Matthias Staufenbiel; Lary C Walker; Mathias Jucker
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-21       Impact factor: 11.205

Review 8.  The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.

Authors:  John Hardy; Dennis J Selkoe
Journal:  Science       Date:  2002-07-19       Impact factor: 47.728

Review 9.  Molecular mechanisms of prion pathogenesis.

Authors:  Adriano Aguzzi; Christina Sigurdson; Mathias Heikenwaelder
Journal:  Annu Rev Pathol       Date:  2008       Impact factor: 23.472

10.  Repetitive immunization enhances the susceptibility of mice to peripherally administered prions.

Authors:  Juliane Bremer; Mathias Heikenwalder; Johannes Haybaeck; Cinzia Tiberi; Nike Julia Krautler; Michael O Kurrer; Adriano Aguzzi
Journal:  PLoS One       Date:  2009-09-25       Impact factor: 3.240
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  255 in total

Review 1.  Intercellular (mis)communication in neurodegenerative disease.

Authors:  Gwenn A Garden; Albert R La Spada
Journal:  Neuron       Date:  2012-03-08       Impact factor: 17.173

2.  A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease.

Authors:  Rashid Deane; Itender Singh; Abhay P Sagare; Robert D Bell; Nathan T Ross; Barbra LaRue; Rachal Love; Sheldon Perry; Nicole Paquette; Richard J Deane; Meenakshisundaram Thiyagarajan; Troy Zarcone; Gunter Fritz; Alan E Friedman; Benjamin L Miller; Berislav V Zlokovic
Journal:  J Clin Invest       Date:  2012-03-12       Impact factor: 14.808

Review 3.  Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders.

Authors:  Berislav V Zlokovic
Journal:  Nat Rev Neurosci       Date:  2011-11-03       Impact factor: 34.870

Review 4.  Synapses and Alzheimer's disease.

Authors:  Morgan Sheng; Bernardo L Sabatini; Thomas C Südhof
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-05-01       Impact factor: 10.005

Review 5.  Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.

Authors:  Colin L Masters; Dennis J Selkoe
Journal:  Cold Spring Harb Perspect Med       Date:  2012-06       Impact factor: 6.915

6.  Cell biology. A unifying role for prions in neurodegenerative diseases.

Authors:  Stanley B Prusiner
Journal:  Science       Date:  2012-06-22       Impact factor: 47.728

Review 7.  Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis.

Authors:  M T Gentile; M G Reccia; P P Sorrentino; E Vitale; G Sorrentino; A A Puca; L Colucci-D'Amato
Journal:  Mol Neurobiol       Date:  2012-05-31       Impact factor: 5.590

8.  Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy.

Authors:  Michiyo Iba; Jing L Guo; Jennifer D McBride; Bin Zhang; John Q Trojanowski; Virginia M-Y Lee
Journal:  J Neurosci       Date:  2013-01-16       Impact factor: 6.167

Review 9.  The neurodegeneration in Alzheimer disease and the prion protein.

Authors:  Gianluigi Forloni; Alessandra Sclip; Tiziana Borsello; Claudia Balducci
Journal:  Prion       Date:  2013-01-01       Impact factor: 3.931

10.  Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice.

Authors:  Jasmin Mahler; Jose Morales-Corraliza; Julia Stolz; Angelos Skodras; Rebecca Radde; Carmen C Duma; Yvonne S Eisele; Matthew J Mazzella; Harrison Wong; William E Klunk; K Peter R Nilsson; Matthias Staufenbiel; Paul M Mathews; Mathias Jucker; Bettina M Wegenast-Braun
Journal:  Neurobiol Aging       Date:  2015-03-25       Impact factor: 4.673
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