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Literature DB >> 20951805

DNA replication fidelity and cancer.

Bradley D Preston¹, Tina M Albertson, Alan J Herr.

Abstract

Cancer is fueled by mutations and driven by adaptive selection. Normal cells avoid deleterious mutations by replicating their genomes with extraordinary accuracy. Here we review the pathways governing DNA replication fidelity and discuss evidence implicating replication errors (point mutation instability or PIN) in carcinogenesis.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2010 PMID： 20951805 PMCID： PMC2993855 DOI： 10.1016/j.semcancer.2010.10.009

Source DB: PubMed Journal: Semin Cancer Biol ISSN： 1044-579X Impact factor: 15.707

234 in total

1. Random mutations, selected mutations: A PIN opens the door to new genetic landscapes.

Authors: Christoph A Klein
Journal: Proc Natl Acad Sci U S A Date: 2006-11-20 Impact factor: 11.205

Review 2. Polymerase dynamics at the eukaryotic DNA replication fork.

Authors: Peter M J Burgers
Journal: J Biol Chem Date: 2008-10-03 Impact factor: 5.157

Review 3. Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity.

Authors: James E Cleaver; Ernest T Lam; Ingrid Revet
Journal: Nat Rev Genet Date: 2009-10-07 Impact factor: 53.242

4. Human cancers express a mutator phenotype.

Authors: Jason H Bielas; Keith R Loeb; Brian P Rubin; Lawrence D True; Lawrence A Loeb
Journal: Proc Natl Acad Sci U S A Date: 2006-11-15 Impact factor: 11.205

5. A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.

Authors: Farid A Kadyrov; Jochen Genschel; Yanan Fang; Elisabeth Penland; Winfried Edelmann; Paul Modrich
Journal: Proc Natl Acad Sci U S A Date: 2009-05-06 Impact factor: 11.205

Review 6. Mouse models of colon cancer.

Authors: Makoto Mark Taketo; Winfried Edelmann
Journal: Gastroenterology Date: 2009-03 Impact factor: 22.682

Review 7. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications.

Authors: H T Lynch; P M Lynch; S J Lanspa; C L Snyder; J F Lynch; C R Boland
Journal: Clin Genet Date: 2009-07 Impact factor: 4.438

8. Cancer genome sequencing--an interim analysis.

Authors: Edward J Fox; Jesse J Salk; Lawrence A Loeb
Journal: Cancer Res Date: 2009-06-09 Impact factor: 12.701

9. DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.

Authors: Tina M Albertson; Masanori Ogawa; James M Bugni; Laura E Hays; Yang Chen; Yanping Wang; Piper M Treuting; John A Heddle; Robert E Goldsby; Bradley D Preston
Journal: Proc Natl Acad Sci U S A Date: 2009-09-24 Impact factor: 11.205

10. Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors.

Authors: Tahir H Tahirov; Kira S Makarova; Igor B Rogozin; Youri I Pavlov; Eugene V Koonin
Journal: Biol Direct Date: 2009-03-18 Impact factor: 4.540

66 in total

Review 1. DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair.

Authors: Iwona J Fijalkowska; Roel M Schaaper; Piotr Jonczyk
Journal: FEMS Microbiol Rev Date: 2012-04-05 Impact factor: 16.408

2. Point mutation instability (PIN) mutator phenotype as model for true back mutations seen in hereditary tyrosinemia type 1 - a hypothesis.

Authors: Etresia van Dyk; Pieter J Pretorius
Journal: J Inherit Metab Dis Date: 2011-10-15 Impact factor: 4.982

DNA replication fidelity and cancer.

1. Random mutations, selected mutations: A PIN opens the door to new genetic landscapes.

Review 2. Polymerase dynamics at the eukaryotic DNA replication fork.

Review 3. Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity.

4. Human cancers express a mutator phenotype.

5. A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.

Review 6. Mouse models of colon cancer.

Review 7. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications.

8. Cancer genome sequencing--an interim analysis.

9. DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.

10. Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors.

Review 1. DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair.

2. Point mutation instability (PIN) mutator phenotype as model for true back mutations seen in hereditary tyrosinemia type 1 - a hypothesis.

Review 3. Replicating damaged DNA in eukaryotes.

4. The landscape of microsatellite instability in colorectal and endometrial cancer genomes.

5. Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine.

Review 6. Personalized Oncology Meets Immunology: The Path toward Precision Immunotherapy.

7. Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit.

8. Mismatch repair hMSH2, hMLH1, hMSH6 and hPMS2 mRNA expression profiles in precancerous and cancerous urothelium.

9. Mass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cells.

Review 10. DNA polymerase delta in DNA replication and genome maintenance.