Literature DB >> 20886485

A "radical dance" in thiamin biosynthesis: mechanistic analysis of the bacterial hydroxymethylpyrimidine phosphate synthase.

Abhishek Chatterjee1, Amrita B Hazra, Sameh Abdelwahed, David G Hilmey, Tadhg P Begley.   

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Year:  2010        PMID： 20886485      PMCID： PMC3147014          DOI： 10.1002/anie.201003419

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  18 in total

Review 1.  Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions.

Authors:  Frank Jordan
Journal:  Nat Prod Rep       Date:  2003-04       Impact factor: 13.423

Review 2.  Cofactor biosynthesis: an organic chemist's treasure trove.

Authors:  Tadhg P Begley
Journal:  Nat Prod Rep       Date:  2006-01-04       Impact factor: 13.423

3.  Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis.

Authors:  Abhishek Chatterjee; Christopher T Jurgenson; Frank C Schroeder; Steven E Ealick; Tadhg P Begley
Journal:  J Am Chem Soc       Date:  2006-06-07       Impact factor: 15.419

4.  Biosynthesis of the pyrimidine moiety of thiamine. A new route of pyrimidine biosynthesis involving purine intermediates.

Authors:  P C Newell; R G Tucker
Journal:  Biochem J       Date:  1968-01       Impact factor: 3.857

5.  Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods.

Authors:  H J Sofia; G Chen; B G Hetzler; J F Reyes-Spindola; N E Miller
Journal:  Nucleic Acids Res       Date:  2001-03-01       Impact factor: 16.971

6.  Biosynthesis of the thiamin pyrimidine: the reconstitution of a remarkable rearrangement reaction.

Authors:  Brian G Lawhorn; Ryan A Mehl; Tadhg P Begley
Journal:  Org Biomol Chem       Date:  2004-08-11       Impact factor: 3.876

7.  Carbon monoxide dehydrogenase from Rhodospirillum rubrum.

Authors:  D Bonam; S A Murrell; P W Ludden
Journal:  J Bacteriol       Date:  1984-08       Impact factor: 3.490

8.  Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site.

Authors:  M Frey; M Rothe; A F Wagner; J Knappe
Journal:  J Biol Chem       Date:  1994-04-29       Impact factor: 5.157

Review 9.  Structural biology of enzymes of the thiamin biosynthesis pathway.

Authors:  Ethan Settembre; Tadhg P Begley; Steven E Ealick
Journal:  Curr Opin Struct Biol       Date:  2003-12       Impact factor: 6.809

10.  Reaction of AdoMet with ThiC generates a backbone free radical.

Authors:  N Cecilia Martinez-Gomez; Russell R Poyner; Steven O Mansoorabadi; George H Reed; Diana M Downs
Journal:  Biochemistry       Date:  2009-01-20       Impact factor: 3.162
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  26 in total

1.  The thiamine biosynthetic enzyme ThiC catalyzes multiple turnovers and is inhibited by S-adenosylmethionine (AdoMet) metabolites.

Authors:  Lauren D Palmer; Diana M Downs
Journal:  J Biol Chem       Date:  2013-09-06       Impact factor: 5.157

2.  High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana.

Authors:  Sandrine Coquille; Céline Roux; Angad Mehta; Tadhg P Begley; Teresa B Fitzpatrick; Stéphane Thore
Journal:  J Struct Biol       Date:  2013-10-23       Impact factor: 2.867

Review 3.  Radical S-adenosylmethionine (SAM) enzymes in cofactor biosynthesis: a treasure trove of complex organic radical rearrangement reactions.

Authors:  Angad P Mehta; Sameh H Abdelwahed; Nilkamal Mahanta; Dmytro Fedoseyenko; Benjamin Philmus; Lisa E Cooper; Yiquan Liu; Isita Jhulki; Steven E Ealick; Tadhg P Begley
Journal:  J Biol Chem       Date:  2014-12-04       Impact factor: 5.157

Review 4.  Radical S-adenosylmethionine enzymes.

Authors:  Joan B Broderick; Benjamin R Duffus; Kaitlin S Duschene; Eric M Shepard
Journal:  Chem Rev       Date:  2014-01-29       Impact factor: 60.622

5.  Mechanistic Studies on Tryptophan Lyase (NosL): Identification of Cyanide as a Reaction Product.

Authors:  Dhananjay M Bhandari; Dmytro Fedoseyenko; Tadhg P Begley
Journal:  J Am Chem Soc       Date:  2018-01-02       Impact factor: 15.419

Review 6.  Thiamin biosynthesis: still yielding fascinating biological chemistry.

Authors:  Tadhg P Begley; Steven E Ealick; Fred W McLafferty
Journal:  Biochem Soc Trans       Date:  2012-06-01       Impact factor: 5.407

7.  Demonstration That the Radical S-Adenosylmethionine (SAM) Enzyme PqqE Catalyzes de Novo Carbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the Peptide Chaperone PqqD.

Authors:  Ian Barr; John A Latham; Anthony T Iavarone; Teera Chantarojsiri; Jennifer D Hwang; Judith P Klinman
Journal:  J Biol Chem       Date:  2016-03-08       Impact factor: 5.157

8.  A missing enzyme in thiamin thiazole biosynthesis: identification of TenI as a thiazole tautomerase.

Authors:  Amrita B Hazra; Ying Han; Abhishek Chatterjee; Yang Zhang; Rung-Yi Lai; Steven E Ealick; Tadhg P Begley
Journal:  J Am Chem Soc       Date:  2011-05-26       Impact factor: 15.419

9.  Amino-4-imidazolecarboxamide ribotide directly inhibits coenzyme A biosynthesis in Salmonella enterica.

Authors:  Jannell V Bazurto; Diana M Downs
Journal:  J Bacteriol       Date:  2013-12-02       Impact factor: 3.490

10.  Analysis of ThiC variants in the context of the metabolic network of Salmonella enterica.

Authors:  Lauren D Palmer; Michael J Dougherty; Diana M Downs
Journal:  J Bacteriol       Date:  2012-09-07       Impact factor: 3.490
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