Literature DB >> 20870910

Passive cooling for initiation of therapeutic hypothermia in neonatal encephalopathy.

Giles S Kendall1, Andrew Kapetanakis, Nandiran Ratnavel, Denis Azzopardi, Nicola J Robertson.   

Abstract

OBJECTIVE: To determine the feasibility of passive cooling to initiate therapeutic hypothermia before and during transport.
METHODS: Consensus guidelines were developed for passive cooling at the referring hospital and on transport by the London Neonatal Transfer Service. These were evaluated in a prospective study.
RESULTS: Between January and October 2009, 39 infants were referred for therapeutic hypothermia; passive cooling was initiated at the referring hospital in all the cases. Despite guidance, no rectal temperature measurements were taken before arrival of the transfer team. Cooling below target temperature (33°C-34°C) occurred in five babies before the arrival of the transfer team. In two of these infants, active cooling was performed, rectal temperature was not recorded and their temperature was lower than 32°C. Of the remaining 37 babies, 33 (89%) demonstrated a reduction in core temperature with passive cooling alone. The percentage of the babies within the temperature range at referral, arrival of the transfer team and arrival at the cooling centre were 0%, 15% and 67%, respectively. On arrival at the cooling centre, four babies had cooled to lower than 33°C by passive cooling alone (32.7°C, 32.6°C, 32.2°C and 32.1°C). Initiation of passive cooling before and during transfer resulted in the therapy starting 4.6 (1.8) h earlier than if initiated on arrival at the cooling centre.
CONCLUSIONS: Passive cooling is a simple and effective technique if portable cooling equipment is unavailable. Rectal temperature monitoring is essential; active cooling methods without core temperature monitoring may lead to overcooling.

Entities:  

Mesh:

Year:  2010        PMID: 20870910     DOI: 10.1136/adc.2010.187211

Source DB:  PubMed          Journal:  Arch Dis Child Fetal Neonatal Ed        ISSN: 1359-2998            Impact factor:   5.747


  18 in total

1.  The baby cooling project of Japan to implement evidence-based neonatal cooling.

Authors:  Osuke Iwata; Toshiki Takenouchi; Sachiko Iwata; Makoto Nabetani; Takeo Mukai; Jun Shibasaki; Kennosuke Tsuda; Takuya Tokuhisa; Hisanori Sobajima; Masanori Tamura
Journal:  Ther Hypothermia Temp Manag       Date:  2014-12       Impact factor: 1.286

2.  Safety and Short-Term Outcomes of Therapeutic Hypothermia in Preterm Neonates 34-35 Weeks Gestational Age with Hypoxic-Ischemic Encephalopathy.

Authors:  Rakesh Rao; Shamik Trivedi; Zachary Vesoulis; Steve M Liao; Christopher D Smyser; Amit M Mathur
Journal:  J Pediatr       Date:  2016-12-13       Impact factor: 4.406

3.  Passive therapeutic hypothermia during ambulance and helicopter secondary neonatal transport in neonates with hypoxic brain injury: a 10-year retrospective survey.

Authors:  Manca Leben; Manca Nolimal; Ivan Vidmar; Štefan Grosek
Journal:  Childs Nerv Syst       Date:  2018-07-18       Impact factor: 1.475

4.  Comparison of selective head cooling therapy and whole body cooling therapy in newborns with hypoxic ischemic encephalopathy: short term results.

Authors:  Aytuğ Atıcı; Yalçın Çelik; Selvi Gülaşı; Ali Haydar Turhan; Çetin Okuyaz; Mehmet Ali Sungur
Journal:  Turk Pediatri Ars       Date:  2015-03-01

Review 5.  Cooling for newborns with hypoxic ischaemic encephalopathy.

Authors:  Susan E Jacobs; Marie Berg; Rod Hunt; William O Tarnow-Mordi; Terrie E Inder; Peter G Davis
Journal:  Cochrane Database Syst Rev       Date:  2013-01-31

6.  Passive cooling during transport of asphyxiated term newborns.

Authors:  D O'Reilly; M Labrecque; M O'Melia; J Bacic; A Hansen; J S Soul
Journal:  J Perinatol       Date:  2012-11-15       Impact factor: 2.521

7.  Therapeutic hypothermia for neonatal encephalopathy.

Authors:  Seetha Shankaran
Journal:  Curr Treat Options Neurol       Date:  2012-12       Impact factor: 3.598

Review 8.  Current status of hypothermia for hypoxemic ischemia of the newborn.

Authors:  Seetha Shankaran
Journal:  Indian J Pediatr       Date:  2014-05-13       Impact factor: 1.967

9.  Body temperature, heart rate and long-term outcome of cooled infants: an observational study.

Authors:  Kennosuke Tsuda; Jun Shibasaki; Tetsuya Isayama; Akihito Takeuchi; Takeo Mukai; Tomoaki Ioroi; Akihito Takahashi; Hiroyuki Sano; Nanae Yutaka; Sachiko Iwata; Makoto Nabetani; Hisanori Sobajima; Shigeharu Hosono; Masanori Tamura; Osuke Iwata
Journal:  Pediatr Res       Date:  2021-04-12       Impact factor: 3.756

10.  Initiation of passive cooling at referring centre is most predictive of achieving early therapeutic hypothermia in asphyxiated newborns.

Authors:  Brigitte Lemyre; Linh Ly; Vann Chau; Anil Chacko; Nicholas Barrowman; Hilary Whyte; Steven P Miller
Journal:  Paediatr Child Health       Date:  2017-05-23       Impact factor: 2.253

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