Literature DB >> 30022316

Passive therapeutic hypothermia during ambulance and helicopter secondary neonatal transport in neonates with hypoxic brain injury: a 10-year retrospective survey.

Manca Leben1, Manca Nolimal1, Ivan Vidmar2, Štefan Grosek3,4,5.   

Abstract

BACKGROUND: Therapeutic hypothermia is a method of treatment in newborns with hypoxic ischemic encephalopathy. Hypothermia should be initiated no later than 6 h after birth. The purpose of this study was to evaluate the quality of the passive therapeutic cooling during neonatal transport.
PURPOSE: The study aims to evaluate the efficiency of our transport in maintenance of target body temperature during transport.
METHODS: We conducted a 10-year retrospective study in neonates, transported by helicopter or ambulance, who received therapeutic passive-induced hypothermia during transport to the Department of Pediatric Surgery and Intensive Therapy at the University Medical Centre Ljubljana between September 1, 2006, and December 31, 2016.
RESULTS: Out of 68 transported newborns, 57 met the criteria for therapeutic induced hypothermia. Eight out of 51 (15.7%) were within therapeutic temperature zone before start of transport while 30 out of 57 (52.6%) were within therapeutic temperature zone at the end of transport. There was a negative correlation between the duration of transport and temperature at the admission (ρ = - 0.306; p = 0.026). A positive correlation was found between the body temperature before and at the end of transport (ρ = 0.410; p = 0,003). A positive correlation between axillary and rectal temperature on admission was found (ρ = 0,832; p < 0,0005). The type of transport, meteorological season, or gender differences did not affect any of measured parameters. Newborns who received chest compression had lower temperature.
CONCLUSION: Therapeutic temperature zone during transport was achieved in 52.6% of transported neonates. Axillary temperature positively correlated with rectal temperature on admission.

Entities:  

Keywords:  Hypothermia; Hypoxia; Neonate; Transportation

Mesh:

Year:  2018        PMID: 30022316     DOI: 10.1007/s00381-018-3914-7

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  31 in total

1.  Therapeutic hypothermia during neonatal transport: current practices in California.

Authors:  Vishnu Priya Akula; Alexis S Davis; Jeffery B Gould; Krisa Van Meurs
Journal:  Am J Perinatol       Date:  2011-12-05       Impact factor: 1.862

2.  Techniques for therapeutic hypothermia during transport and in hospital for perinatal asphyxial encephalopathy.

Authors:  Nicola J Robertson; Giles S Kendall; Sudhin Thayyil
Journal:  Semin Fetal Neonatal Med       Date:  2010-06-19       Impact factor: 3.926

Review 3.  Interventions for perinatal hypoxic-ischemic encephalopathy.

Authors:  R C Vannucci; J M Perlman
Journal:  Pediatrics       Date:  1997-12       Impact factor: 7.124

4.  Therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy is associated with short-term reduction of seizures after discharge from the neonatal intensive care unit.

Authors:  Suman Ghosh; Lily Tran; Jonathan J Shuster; Mary L Zupanc
Journal:  Childs Nerv Syst       Date:  2016-12-17       Impact factor: 1.475

5.  Efficacy of passive hypothermia and adverse events during transport of asphyxiated newborns according to the severity of hypoxic-ischemic encephalopathy.

Authors:  Nuria Carreras; Miguel Alsina; Ana Alarcon; Gemma Arca-Díaz; Thais Agut; Alfredo García-Alix
Journal:  J Pediatr (Rio J)       Date:  2017-08-18       Impact factor: 2.197

Review 6.  Outcomes of hypoxic-ischemic encephalopathy in neonates treated with hypothermia.

Authors:  Seetha Shankaran
Journal:  Clin Perinatol       Date:  2014-03       Impact factor: 3.430

7.  Passive cooling during transport of asphyxiated term newborns.

Authors:  D O'Reilly; M Labrecque; M O'Melia; J Bacic; A Hansen; J S Soul
Journal:  J Perinatol       Date:  2012-11-15       Impact factor: 2.521

Review 8.  Effects of hypothermia on energy metabolism in Mammalian central nervous system.

Authors:  Maria Erecinska; Marianne Thoresen; Ian A Silver
Journal:  J Cereb Blood Flow Metab       Date:  2003-05       Impact factor: 6.200

9.  Time is brain: starting therapeutic hypothermia within three hours after birth improves motor outcome in asphyxiated newborns.

Authors:  Marianne Thoresen; James Tooley; Xun Liu; Sally Jary; Peter Fleming; Karen Luyt; Anoopam Jain; Pamela Cairns; David Harding; Hemmen Sabir
Journal:  Neonatology       Date:  2013-09-12       Impact factor: 4.035

10.  Passive cooling for initiation of therapeutic hypothermia in neonatal encephalopathy.

Authors:  Giles S Kendall; Andrew Kapetanakis; Nandiran Ratnavel; Denis Azzopardi; Nicola J Robertson
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2010-09-24       Impact factor: 5.747

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  1 in total

1.  Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia.

Authors:  Wojciech Walas; Dominika Bandoła; Ziemowit Ostrowski; Marek Rojczyk; Anna Mączko; Zenon Halaba; Andrzej J Nowak
Journal:  Sci Rep       Date:  2020-12-17       Impact factor: 4.379

  1 in total

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