OBJECTIVE: We conducted this study to evaluate the clinical impact of early enteral nutrition (EN) on in-hospital mortality and outcome in patients with critical hypertensive intracerebral hemorrhage (ICH). METHODS: We retrospectively analyzed 123 ICH patients with Glasgow Coma Scale (GCS) score of 3-12. We divided the subjects into two groups : early EN group (< 48 hours, n = 89) and delayed EN group (≥ 48 hours, n = 34). Body weight, total intake and output, serum albumin, C-reactive protein, infectious complications, morbidity at discharge and in-hospital mortality were compared with statistical analysis. RESULTS: The incidence of nosocomial pneumonia and length of intensive care unit stay were significantly lower in the early EN group than in the delayed EN group (p < 0.05). In-hospital mortality was less in the early EN group than in the delayed EN group (10.1% vs. 35.3%, respectively; p = 0.001). By multivariate analysis, early EN [odds ratio (OR) 0.229, 95% CI : 0.066-0.793], nosocomial pneumonia (OR = 5.381, 95% CI : 1.621-17.865) and initial GCS score (OR = 1.482 95% CI : 1.160-1.893) were independent predictors of in-hospital mortality in patients with critical hypertensive ICH. CONCLUSION: These findings indicate that early EN is an important predictor of outcome in patients with critical hypertensive ICH.
OBJECTIVE: We conducted this study to evaluate the clinical impact of early enteral nutrition (EN) on in-hospital mortality and outcome in patients with critical hypertensive intracerebral hemorrhage (ICH). METHODS: We retrospectively analyzed 123 ICHpatients with Glasgow Coma Scale (GCS) score of 3-12. We divided the subjects into two groups : early EN group (< 48 hours, n = 89) and delayed EN group (≥ 48 hours, n = 34). Body weight, total intake and output, serum albumin, C-reactive protein, infectious complications, morbidity at discharge and in-hospital mortality were compared with statistical analysis. RESULTS: The incidence of nosocomial pneumonia and length of intensive care unit stay were significantly lower in the early EN group than in the delayed EN group (p < 0.05). In-hospital mortality was less in the early EN group than in the delayed EN group (10.1% vs. 35.3%, respectively; p = 0.001). By multivariate analysis, early EN [odds ratio (OR) 0.229, 95% CI : 0.066-0.793], nosocomial pneumonia (OR = 5.381, 95% CI : 1.621-17.865) and initial GCS score (OR = 1.482 95% CI : 1.160-1.893) were independent predictors of in-hospital mortality in patients with critical hypertensive ICH. CONCLUSION: These findings indicate that early EN is an important predictor of outcome in patients with critical hypertensive ICH.
Authors: Juan C Montejo; Teodoro Grau; Jose Acosta; Sergio Ruiz-Santana; Mercé Planas; Abelardo García-De-Lorenzo; Alfonso Mesejo; Manuel Cervera; Carmen Sánchez-Alvarez; Rafael Núñez-Ruiz; Jorge López-Martínez Journal: Crit Care Med Date: 2002-04 Impact factor: 7.598
Authors: Christoph Pachler; Johannes Plank; Heinz Weinhandl; Ludovic J Chassin; Malgorzata E Wilinska; Roman Kulnik; Peter Kaufmann; Karl-Heinz Smolle; Ernst Pilger; Thomas R Pieber; Martin Ellmerer; Roman Hovorka Journal: Intensive Care Med Date: 2008-02-23 Impact factor: 17.440
Authors: Annika Reintam Blaser; Joel Starkopf; Waleed Alhazzani; Mette M Berger; Michael P Casaer; Adam M Deane; Sonja Fruhwald; Michael Hiesmayr; Carole Ichai; Stephan M Jakob; Cecilia I Loudet; Manu L N G Malbrain; Juan C Montejo González; Catherine Paugam-Burtz; Martijn Poeze; Jean-Charles Preiser; Pierre Singer; Arthur R H van Zanten; Jan De Waele; Julia Wendon; Jan Wernerman; Tony Whitehouse; Alexander Wilmer; Heleen M Oudemans-van Straaten Journal: Intensive Care Med Date: 2017-02-06 Impact factor: 17.440