PURPOSE: To test our hypothesis that distension and displacement in various segments of the healthy thoracic aorta are significant and can be predicted based on clinical characteristics. MATERIALS AND METHODS: Sixty-one Caucasian volunteers without cardiovascular disease (49 ± 16 years, range 19-82; 28 men, 33 women) divided into two age groups (A: <50, B: ≥ 50 years) underwent 1.5-T MRI. ECG-gated dynamic data sets were acquired at five locations perpendicular to the thoracic aorta. Aortic distension and Centre of Mass (CoM) displacement were determined as percentages of diastolic aortic diameter. A multiple linear regression model including age group, gender, location, mean arterial blood pressure, heart rate and body mass index was tested. RESULTS: Mean aortic distension averaged over all locations was 11.2 ± 4.1% (age group A) and 6.7 ± 3.3% (age group B), mean displacement 15.1 ± 8.3% (A) and 11.0 ± 6.2% (B). Systolic and diastolic aortic diameter and CoM position significantly differed at all locations (p<0.001). Distension and displacement could be predicted based on the regression model (p<0.001). Age group A and women exhibited significantly greater distension and displacement compared to age group B (p<0.001) and men (p<0.01), respectively. Distension increased, displacement decreased from proximal to distal. CONCLUSION: Distension and translational displacement are significant at all levels of the thoracic aorta and can be predicted based on clinical characteristics.
PURPOSE: To test our hypothesis that distension and displacement in various segments of the healthy thoracic aorta are significant and can be predicted based on clinical characteristics. MATERIALS AND METHODS: Sixty-one Caucasian volunteers without cardiovascular disease (49 ± 16 years, range 19-82; 28 men, 33 women) divided into two age groups (A: <50, B: ≥ 50 years) underwent 1.5-T MRI. ECG-gated dynamic data sets were acquired at five locations perpendicular to the thoracic aorta. Aortic distension and Centre of Mass (CoM) displacement were determined as percentages of diastolic aortic diameter. A multiple linear regression model including age group, gender, location, mean arterial blood pressure, heart rate and body mass index was tested. RESULTS: Mean aortic distension averaged over all locations was 11.2 ± 4.1% (age group A) and 6.7 ± 3.3% (age group B), mean displacement 15.1 ± 8.3% (A) and 11.0 ± 6.2% (B). Systolic and diastolic aortic diameter and CoM position significantly differed at all locations (p<0.001). Distension and displacement could be predicted based on the regression model (p<0.001). Age group A and women exhibited significantly greater distension and displacement compared to age group B (p<0.001) and men (p<0.01), respectively. Distension increased, displacement decreased from proximal to distal. CONCLUSION: Distension and translational displacement are significant at all levels of the thoracic aorta and can be predicted based on clinical characteristics.
Authors: Tim F Weber; Tobias Müller; Andreas Biesdorf; Stefan Wörz; Fabian Rengier; Tobias Heye; Tim Holland-Letz; Karl Rohr; Hans-Ulrich Kauczor; Hendrik von Tengg-Kobligk Journal: Int J Cardiovasc Imaging Date: 2013-10-18 Impact factor: 2.357
Authors: Roel L F van der Palen; Arno A W Roest; Pieter J van den Boogaard; Albert de Roos; Nico A Blom; Jos J M Westenberg Journal: MAGMA Date: 2018-05-26 Impact factor: 2.310
Authors: Joe F Juffermans; Jos J M Westenberg; Pieter J van den Boogaard; Arno A W Roest; Hans C van Assen; Roel L F van der Palen; Hildo J Lamb Journal: J Magn Reson Imaging Date: 2020-11-11 Impact factor: 4.813