Literature DB >> 208460

Inactivation of herpes simplex viruses by nonionic surfactants.

S S Asculai, M T Weis, M W Rancourt, A B Kupferberg.   

Abstract

Nonionic surface-active agents possessing ether or amide linkages between the hydrophillic and hydrophobic portions of the molecule rapidly inactivated the infectivity of herpes simplex viruses. The activity stemmed from the ability of nonionic surfactants to dissolve lipid-containing membranes. This was confirmed by observing surfactant destruction of mammalian cell plasma membranes and herpes simplex virus envelopes. Proprietary vaginal contraceptive formulations containing nonionic surfactants also inactivated herpes simplex virus infectivity. This observation suggests that nonionic surfactants in appropriate formulation could effectively prevent herpes simplex virus transmission.

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Year:  1978        PMID： 208460      PMCID： PMC352310          DOI： 10.1128/AAC.13.4.686

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  13 in total

1.  Virucidal effect of certain chemical contraceptives on Type 2 herpesvirus.

Authors:  B Singh; B Posti; J C Cutler
Journal:  Am J Obstet Gynecol       Date:  1976-10-15       Impact factor: 8.661

2.  Transformation of mammalian cells by DNA-containing viruses following photodynamic inactivation.

Authors:  F Rapp; J L Li; M Jerkofsky
Journal:  Virology       Date:  1973-10       Impact factor: 3.616

3.  Resistance of hamster cells transformed by herpes simplex virus type 2 to superinfection by herpes simplex viruses.

Authors:  E Doller; R Duff; F Rapp
Journal:  Intervirology       Date:  1973       Impact factor: 1.763

4.  Antibody to genital herpes simplex virus: association with cervical atypia and carcinoma in situ.

Authors:  L Aurelian; I Royston; H J Davis
Journal:  J Natl Cancer Inst       Date:  1970-09       Impact factor: 13.506

5.  Herpesvirus type 2 and cervical carcinoma.

Authors:  J L Melnick; W E Rawls
Journal:  Ann N Y Acad Sci       Date:  1970-10-30       Impact factor: 5.691

6.  Genital herpetic infection. Association with cervical dysplasia and carcinoma.

Authors:  Z M Naib; A J Nahmias; W E Josey; J H Kramer
Journal:  Cancer       Date:  1969-04       Impact factor: 6.860

7.  Herpes simplex virus products in productive and abortive infection. 3. Differentiation of infectious virus derived from nucleus and cytoplasm with respect to stability and size.

Authors:  S B Spring; B Roizman
Journal:  J Virol       Date:  1968-10       Impact factor: 5.103

8.  Soluble membrane antigens of lip and cervical carcinomas: reactivity with antibody for herpesvirus nonvirion antigens.

Authors:  A C Hollinshead; G Tarro
Journal:  Science       Date:  1973-02-16       Impact factor: 47.728

9.  Herpes simplex and herpes genitalis viruses in etiology of some human cancers.

Authors:  A B Sabin; G Tarro
Journal:  Proc Natl Acad Sci U S A       Date:  1973-11       Impact factor: 11.205

10.  Observations on the mode of release of herpes virus from infected HeLa cells.

Authors:  M A EPSTEIN
Journal:  J Cell Biol       Date:  1962-03       Impact factor: 10.539
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  20 in total

1.  Thermoreversible gel formulations containing sodium lauryl sulfate or n-Lauroylsarcosine as potential topical microbicides against sexually transmitted diseases.

Authors:  S Roy; P Gourde; J Piret; A Désormeaux; J Lamontagne; C Haineault; R F Omar; M G Bergeron
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

2.  Vaginal formulations of carrageenan protect mice from herpes simplex virus infection.

Authors:  V R Zacharopoulos; D M Phillips
Journal:  Clin Diagn Lab Immunol       Date:  1997-07

3.  Solubilization and in vitro spermicidal assessment of nonoxynol-9 and selected fractions using rabbit spermatozoa.

Authors:  B A Walter; A A Hawi; P M Zavos; G A Digenis
Journal:  Pharm Res       Date:  1991-03       Impact factor: 4.200

4.  Evaluation of an antimicrobial soap formula for virucidal efficacy in vitro against human immunodeficiency virus in a blood-virus mixture.

Authors:  G C Lavelle; S L Gubbe; J L Neveaux; B J Bowden
Journal:  Antimicrob Agents Chemother       Date:  1989-12       Impact factor: 5.191

5.  Nonoxinol 9 and HIV infection.

Authors:  D J Jeffries
Journal:  Br Med J (Clin Res Ed)       Date:  1988-06-25

Review 6.  Non-specific microbicide product development: then and now.

Authors:  Joseph W Romano; Melissa Robbiani; Gustavo F Doncel; Thomas Moench
Journal:  Curr HIV Res       Date:  2012-01-01       Impact factor: 1.581

7.  Hydrogels containing monocaprin have potent microbicidal activities against sexually transmitted viruses and bacteria in vitro.

Authors:  H Thormar; G Bergsson; E Gunnarsson; G Georgsson; M Witvrouw; O Steingrímsson; E De Clercq; T Kristmundsdóttir
Journal:  Sex Transm Infect       Date:  1999-06       Impact factor: 3.519

8.  Synergistic effect of human leukocyte interferon and nonoxynol 9 against herpes simplex virus type 2.

Authors:  F Rapp; H Wrzos
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191

9.  Chlamydia trachomatis laboratory strains versus recent clinical isolates: implications for routine microbicide testing.

Authors:  M C Skinner; W E Stamm; M L Lampe
Journal:  Antimicrob Agents Chemother       Date:  2009-02-02       Impact factor: 5.191

10.  In vitro activity of nonoxynol 9 on HeLa 229 cells and primary monkey cervical epithelial cells infected with Chlamydia trachomatis.

Authors:  D L Patton; S K Wang; C C Kuo
Journal:  Antimicrob Agents Chemother       Date:  1992-07       Impact factor: 5.191
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