Literature DB >> 20845980

Verticilactam, a new macrolactam isolated from a microbial metabolite fraction library.

Toshihiko Nogawa1, Akiko Okano, Shunji Takahashi, Masakazu Uramoto, Hideaki Konno, Tamio Saito, Hiroyuki Osada.   

Abstract

Systematic isolation of microbial metabolites has been performed to construct microbial metabolite libraries or fraction libraries. A novel macrolactam, verticilactam (1), was isolated from a library of Streptomyces spiroverticillatus JC-8444. The structure was determined on the basis of NMR and mass spectrometric measurements. 1 had a unique 16-membered macrolactam skeleton including a β-keto-amide moiety.

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Year:  2010        PMID： 20845980     DOI： 10.1021/ol1018618

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Unantimycin A, a new neoantimycin analog isolated from a microbial metabolite fraction library.

Authors:  Chung Liang Lim; Toshihiko Nogawa; Akiko Okano; Yushi Futamura; Makoto Kawatani; Shunji Takahashi; Darah Ibrahim; Hiroyuki Osada
Journal:  J Antibiot (Tokyo)       Date:  2015-12-09       Impact factor: 2.649

2.  RK-270A-C, new oxindole derivatives isolated from a microbial metabolites fraction library of Streptomyces sp. RK85-270.

Authors:  Jun-Pil Jang; Toshihiko Nogawa; Masakazu Uramoto; Akiko Okano; Yushi Futamura; Takeshi Shimizu; Shunji Takahashi; Jae-Hyuk Jang; Jong Seog Ahn; Hiroyuki Osada
Journal:  J Antibiot (Tokyo)       Date:  2014-10-15       Impact factor: 2.649

3.  Opantimycin A, a new metabolite isolated from Streptomyces sp. RK88-1355.

Authors:  Toshihiko Nogawa; Akiko Okano; Chung Liang Lim; Yushi Futamura; Takeshi Shimizu; Shunji Takahashi; Darah Ibrahim; Hiroyuki Osada
Journal:  J Antibiot (Tokyo)       Date:  2016-09-07       Impact factor: 2.649

4.  Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058.

Authors:  Toshihiko Nogawa; Naoki Kato; Takeshi Shimizu; Akiko Okano; Yushi Futamura; Shunji Takahashi; Hiroyuki Osada
Journal:  J Antibiot (Tokyo)       Date:  2017-09-13       Impact factor: 2.649

5.  Macrotermycins A-D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39.

Authors:  Christine Beemelmanns; Timothy R Ramadhar; Ki Hyun Kim; Jonathan L Klassen; Shugeng Cao; Thomas P Wyche; Yanpeng Hou; Michael Poulsen; Tim S Bugni; Cameron R Currie; Jon Clardy
Journal:  Org Lett       Date:  2017-02-16       Impact factor: 6.005

Review 6.  Polyene Macrolactams from Marine and Terrestrial Sources: Structure, Production Strategies, Biosynthesis and Bioactivities.

Authors:  Wei Zhao; Hong Jiang; Xiao-Wan Liu; Jian Zhou; Bin Wu
Journal:  Mar Drugs       Date:  2022-05-27       Impact factor: 6.085

7.  Novel Macrolactams from a Deep-Sea-Derived Streptomyces Species.

Authors:  Pei Wang; Dongyang Wang; Rongxin Zhang; Yi Wang; Fandong Kong; Peng Fu; Weiming Zhu
Journal:  Mar Drugs       Date:  2020-12-29       Impact factor: 5.118
  7 in total

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