Literature DB >> 20842675

Synthesis and molecular modeling of a nitrogen mustard DNA interstrand crosslink.

Angelo Guainazzi1, Arthur J Campbell, Todor Angelov, Carlos Simmerling, Orlando D Schärer.   

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Year:  2010        PMID： 20842675      PMCID： PMC4870935          DOI： 10.1002/chem.201002041

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


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  23 in total

1.  Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer.

Authors:  C Hofr; V Brabec
Journal:  J Biol Chem       Date:  2000-12-04       Impact factor: 5.157

Review 2.  Translesion DNA synthesis polymerases in DNA interstrand crosslink repair.

Authors:  The Vinh Ho; Orlando D Schärer
Journal:  Environ Mol Mutagen       Date:  2010-07       Impact factor: 3.216

3.  Nitrogen mustard therapy; use of methyl-bis (beta-chloroethyl) amine hydrochloride and tris (beta-chloroethyl) amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.

Authors:  L S GOODMAN; M M WINTROBE
Journal:  J Am Med Assoc       Date:  1946-09-21

4.  Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link.

Authors:  J O Ojwang; D A Grueneberg; E L Loechler
Journal:  Cancer Res       Date:  1989-12-01       Impact factor: 12.701

Review 5.  DNA interstrand crosslinks: natural and drug-induced DNA adducts that induce unique cellular responses.

Authors:  Orlando D Schärer
Journal:  Chembiochem       Date:  2005-01       Impact factor: 3.164

6.  A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC).

Authors:  Q Dong; D Barsky; M E Colvin; C F Melius; S M Ludeman; J F Moravek; O M Colvin; D D Bigner; P Modrich; H S Friedman
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-19       Impact factor: 11.205

7.  Synthesis and characterization of DNA containing an N1-2'-deoxyinosine-ethyl-N3-thymidine interstrand cross-link: a structural mimic of the cross-link formed by 1,3-bis-(2-chloroethyl)-1-nitrosourea.

Authors:  Christopher J Wilds; Fei Xu; Anne M Noronha
Journal:  Chem Res Toxicol       Date:  2008-02-08       Impact factor: 3.739

Review 8.  DNA interstrand crosslink repair in mammalian cells: step by step.

Authors:  Parameswary A Muniandy; Jia Liu; Alokes Majumdar; Su-ting Liu; Michael M Seidman
Journal:  Crit Rev Biochem Mol Biol       Date:  2010-02       Impact factor: 8.250

9.  A modified thymine for the synthesis of site-specific thymine-guanine DNA interstrand crosslinks.

Authors:  Jawad Alzeer; Orlando D Schärer
Journal:  Nucleic Acids Res       Date:  2006-08-31       Impact factor: 16.971

10.  The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.

Authors:  Puck Knipscheer; Markus Räschle; Agata Smogorzewska; Milica Enoiu; The Vinh Ho; Orlando D Schärer; Stephen J Elledge; Johannes C Walter
Journal:  Science       Date:  2009-11-12       Impact factor: 47.728
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  20 in total

Review 1.  Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.

Authors:  Blanka Sengerová; Anderson T Wang; Peter J McHugh
Journal:  Cell Cycle       Date:  2011-12-01       Impact factor: 4.534

Review 2.  Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.

Authors:  Angelo Guainazzi; Orlando D Schärer
Journal:  Cell Mol Life Sci       Date:  2010-08-21       Impact factor: 9.261

3.  Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.

Authors:  Yu V Fu; Hasan Yardimci; David T Long; The Vinh Ho; Angelo Guainazzi; Vladimir P Bermudez; Jerard Hurwitz; Antoine van Oijen; Orlando D Schärer; Johannes C Walter
Journal:  Cell       Date:  2011-09-16       Impact factor: 41.582

4.  Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway.

Authors:  Niyo Kato; Yoshitaka Kawasoe; Hannah Williams; Elena Coates; Upasana Roy; Yuqian Shi; Lorena S Beese; Orlando D Schärer; Hong Yan; Max E Gottesman; Tatsuro S Takahashi; Jean Gautier
Journal:  Cell Rep       Date:  2017-10-31       Impact factor: 9.423

5.  Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase.

Authors:  Daniel R Semlow; Jieqiong Zhang; Magda Budzowska; Alexander C Drohat; Johannes C Walter
Journal:  Cell       Date:  2016-09-29       Impact factor: 41.582

6.  Topical nitrogen mustard exposure causes systemic toxic effects in mice.

Authors:  Dinesh G Goswami; Dileep Kumar; Neera Tewari-Singh; David J Orlicky; Anil K Jain; Rama Kant; Raymond C Rancourt; Deepanshi Dhar; Swetha Inturi; Chapla Agarwal; Carl W White; Rajesh Agarwal
Journal:  Exp Toxicol Pathol       Date:  2014-12-04

7.  FANCD2-associated nuclease 1, but not exonuclease 1 or flap endonuclease 1, is able to unhook DNA interstrand cross-links in vitro.

Authors:  Julia Pizzolato; Shivam Mukherjee; Orlando D Schärer; Josef Jiricny
Journal:  J Biol Chem       Date:  2015-07-28       Impact factor: 5.157

8.  Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.

Authors:  Swetha Inturi; Neera Tewari-Singh; Chapla Agarwal; Carl W White; Rajesh Agarwal
Journal:  Mutat Res       Date:  2014-04-13       Impact factor: 2.433

Review 9.  Advances in understanding the complex mechanisms of DNA interstrand cross-link repair.

Authors:  Cheryl Clauson; Orlando D Schärer; Laura Niedernhofer
Journal:  Cold Spring Harb Perspect Biol       Date:  2013-10-01       Impact factor: 10.005

10.  Construction of plasmids containing site-specific DNA interstrand cross-links for biochemical and cell biological studies.

Authors:  Milica Enoiu; The Vinh Ho; David T Long; Johannes C Walter; Orlando D Schärer
Journal:  Methods Mol Biol       Date:  2012
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