Literature DB >> 20833307

Gene regulation: enhancers stepping out of the shadow.

Oliver Hobert1.   

Abstract

The expression of many animal genes has been shown to be controlled by two--rather than one--enhancers with similar regulatory content. Such enhancer redundancy ensures robustness of gene expression under adverse environmental or genetic conditions.
Copyright © 2010 Elsevier Ltd. All rights reserved.

Mesh：

Year:  2010        PMID： 20833307     DOI： 10.1016/j.cub.2010.07.035

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  16 in total

Review 1.  Transcriptional activators and activation mechanisms.

Authors:  Jun Ma
Journal:  Protein Cell       Date:  2011-12-17       Impact factor: 14.870

2.  Evolution of a tissue-specific silencer underlies divergence in the expression of pax2 and pax8 paralogues.

Authors:  Haruki Ochi; Tomoko Tamai; Hiroki Nagano; Akane Kawaguchi; Norihiro Sudou; Hajime Ogino
Journal:  Nat Commun       Date:  2012-05-22       Impact factor: 14.919

Review 3.  Enhancer redundancy in development and disease.

Authors:  Evgeny Z Kvon; Zeba Wunderlich; Rachel Waymack; Mario Gad
Journal:  Nat Rev Genet       Date:  2021-01-12       Impact factor: 53.242

4.  Multiple enhancers associated with ACAN suggest highly redundant transcriptional regulation in cartilage.

Authors:  Gui Hu; Marta Codina; Shannon Fisher
Journal:  Matrix Biol       Date:  2012-07-20       Impact factor: 11.583

5.  Targeted chromatin profiling reveals novel enhancers in Ig H and Ig L chain Loci.

Authors:  Alexander V Predeus; Suhasni Gopalakrishnan; Yue Huang; Jun Tang; Ann J Feeney; Eugene M Oltz; Maxim N Artyomov
Journal:  J Immunol       Date:  2013-12-18       Impact factor: 5.422

6.  Redundant and Cryptic Enhancer Activities of the Drosophila yellow Gene.

Authors:  Gizem Kalay; Jennifer Lachowiec; Ulises Rosas; Mackenzie R Dome; Patricia Wittkopp
Journal:  Genetics       Date:  2019-03-06       Impact factor: 4.562

7.  Transcriptional enhancers in animal development and evolution.

Authors:  Mike Levine
Journal:  Curr Biol       Date:  2010-09-14       Impact factor: 10.834

8.  Shadow enhancers: frequently asked questions about distributed cis-regulatory information and enhancer redundancy.

Authors:  Scott Barolo
Journal:  Bioessays       Date:  2011-11-15       Impact factor: 4.345

9.  Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons.

Authors:  Lucía F Franchini; Rodrigo López-Leal; Sofía Nasif; Paula Beati; Diego M Gelman; Malcolm J Low; Flávio J S de Souza; Marcelo Rubinstein
Journal:  Proc Natl Acad Sci U S A       Date:  2011-08-29       Impact factor: 11.205

10.  A SINE-derived element constitutes a unique modular enhancer for mammalian diencephalic Fgf8.

Authors:  Akiko Nakanishi; Naoki Kobayashi; Asuka Suzuki-Hirano; Hidenori Nishihara; Takeshi Sasaki; Mika Hirakawa; Kenta Sumiyama; Tomomi Shimogori; Norihiro Okada
Journal:  PLoS One       Date:  2012-08-24       Impact factor: 3.240
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