Literature DB >> 22180087

Transcriptional activators and activation mechanisms.

Jun Ma1.   

Abstract

Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase II to the promoter or its elongation. This article examines a few selected issues in understanding activator functions and activation mechanisms.

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Year:  2011        PMID: 22180087      PMCID: PMC4712173          DOI: 10.1007/s13238-011-1101-7

Source DB:  PubMed          Journal:  Protein Cell        ISSN: 1674-800X            Impact factor:   14.870


  148 in total

1.  Enhancement of TBP binding by activators and general transcription factors.

Authors:  X Y Li; A Virbasius; X Zhu; M R Green
Journal:  Nature       Date:  1999-06-10       Impact factor: 49.962

Review 2.  Recognition of specific DNA sequences.

Authors:  C W Garvie; C Wolberger
Journal:  Mol Cell       Date:  2001-11       Impact factor: 17.970

3.  Two "what if" experiments.

Authors:  Mark Ptashne
Journal:  Cell       Date:  2004-01-23       Impact factor: 41.582

Review 4.  Something about SUMO inhibits transcription.

Authors:  Grace Gill
Journal:  Curr Opin Genet Dev       Date:  2005-10       Impact factor: 5.578

5.  Individual stage selector element mutations lead to reciprocal changes in beta- vs. epsilon-globin gene transcription: genetic confirmation of promoter competition during globin gene switching.

Authors:  K P Foley; J D Engel
Journal:  Genes Dev       Date:  1992-05       Impact factor: 11.361

6.  Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein.

Authors:  L Keegan; G Gill; M Ptashne
Journal:  Science       Date:  1986-02-14       Impact factor: 47.728

7.  Short transcripts of the ternary complex provide insight into RNA polymerase II elongational pausing.

Authors:  E B Rasmussen; J T Lis
Journal:  J Mol Biol       Date:  1995-10-06       Impact factor: 5.469

8.  Selectivity, sharing and competitive interactions in the regulation of Hoxb genes.

Authors:  J Sharpe; S Nonchev; A Gould; J Whiting; R Krumlauf
Journal:  EMBO J       Date:  1998-03-16       Impact factor: 11.598

9.  Polymerase II promoter activation: closed complex formation and ATP-driven start site opening.

Authors:  W Wang; M Carey; J D Gralla
Journal:  Science       Date:  1992-01-24       Impact factor: 47.728

Review 10.  LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins.

Authors:  Jacqueline M Matthews; Jane E Visvader
Journal:  EMBO Rep       Date:  2003-12       Impact factor: 8.807

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  13 in total

1.  Evaluating the Drosophila Bicoid morphogen gradient system through dissecting the noise in transcriptional bursts.

Authors:  Feng He; Jie Ren; Wei Wang; Jun Ma
Journal:  Bioinformatics       Date:  2012-02-02       Impact factor: 6.937

2.  A comprehensive and high-resolution genome-wide response of p53 to stress.

Authors:  Gue Su Chang; Xiangyun Amy Chen; Bongsoo Park; Ho Sung Rhee; Pingxin Li; Kang Hoo Han; Tejaswini Mishra; Ka Yim Chan-Salis; Yunfei Li; Ross C Hardison; Yanming Wang; B Franklin Pugh
Journal:  Cell Rep       Date:  2014-07-17       Impact factor: 9.423

3.  A Trihelix Family Transcription Factor Is Associated with Key Genes in Mixed-Linkage Glucan Accumulation.

Authors:  Mingzhu Fan; Klaus Herburger; Jacob K Jensen; Starla Zemelis-Durfee; Federica Brandizzi; Stephen C Fry; Curtis G Wilkerson
Journal:  Plant Physiol       Date:  2018-09-17       Impact factor: 8.340

Review 4.  Perspectives for epigenetic editing in crops.

Authors:  S Selma; D Orzáez
Journal:  Transgenic Res       Date:  2021-04-23       Impact factor: 2.788

Review 5.  Genome-editing tools for stem cell biology.

Authors:  E A Vasileva; O U Shuvalov; A V Garabadgiu; G Melino; N A Barlev
Journal:  Cell Death Dis       Date:  2015-07-23       Impact factor: 8.469

Review 6.  Targeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and Treatment.

Authors:  Rudolph E Willis
Journal:  Int J Mol Sci       Date:  2016-09-14       Impact factor: 5.923

7.  Transcriptional regulation of metabolism in disease: From transcription factors to epigenetics.

Authors:  Liam J Hawkins; Rasha Al-Attar; Kenneth B Storey
Journal:  PeerJ       Date:  2018-06-15       Impact factor: 2.984

8.  A spatial point pattern analysis in Drosophila blastoderm embryos evaluating the potential inheritance of transcriptional states.

Authors:  Feng He; Jun Ma
Journal:  PLoS One       Date:  2013-04-09       Impact factor: 3.240

9.  The dual role of SrbA from Paracoccidioides lutzii: a hypoxic regulator.

Authors:  Lorena Ordones de Sousa; Lucas Nojosa Oliveira; Raphaela Barbosa Naves; André Luiz Araújo Pereira; Kleber Santiago Freitas E Silva; Célia Maria de Almeida Soares; Patrícia de Sousa Lima
Journal:  Braz J Microbiol       Date:  2021-06-19       Impact factor: 2.214

10.  Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity.

Authors:  Abigail E Horn; Jennifer F Kugel; James A Goodrich
Journal:  Nucleic Acids Res       Date:  2016-04-25       Impact factor: 16.971

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