OBJECTIVE: Anxiety is highly comorbid with depression, but little is known about the impact of anxiety disorders on the effectiveness of empirically supported psychotherapies for depression. We examined such outcomes for people with Multiple Sclerosis (MS) and depression, with versus without comorbid anxiety disorders. DESIGN:Participants with MS (N = 102) received 16 weeks of telephone-administered psychotherapy for depression and were followed for one year post-treatment. RESULTS:Participants with comorbid anxiety disorders improved to a similar degree during treatment as those without anxiety disorders. Outcomes during follow-up were mixed, and thus we divided the anxiety diagnoses into distress and fear disorders. The distress disorder (GAD) was associated with elevated anxiety symptoms during and after treatment. In contrast, fear disorders (i.e., panic disorder, agoraphobia, social phobia, specific phobia) were linked to depression, specifically during follow-up, across 3 different measures. CONCLUSIONS:People with GAD receiving treatment for depression may benefit from additional services targeting anxiety more specifically, while those with comorbid fear disorders may benefit from services targeting maintenance of gains after treatment.
RCT Entities:
OBJECTIVE:Anxiety is highly comorbid with depression, but little is known about the impact of anxiety disorders on the effectiveness of empirically supported psychotherapies for depression. We examined such outcomes for people with Multiple Sclerosis (MS) and depression, with versus without comorbid anxiety disorders. DESIGN:Participants with MS (N = 102) received 16 weeks of telephone-administered psychotherapy for depression and were followed for one year post-treatment. RESULTS:Participants with comorbid anxiety disorders improved to a similar degree during treatment as those without anxiety disorders. Outcomes during follow-up were mixed, and thus we divided the anxiety diagnoses into distress and fear disorders. The distress disorder (GAD) was associated with elevated anxiety symptoms during and after treatment. In contrast, fear disorders (i.e., panic disorder, agoraphobia, social phobia, specific phobia) were linked to depression, specifically during follow-up, across 3 different measures. CONCLUSIONS:People with GAD receiving treatment for depression may benefit from additional services targeting anxiety more specifically, while those with comorbid fear disorders may benefit from services targeting maintenance of gains after treatment.
Authors: David C Mohr; Stacey L Hart; Laura Julian; Claudine Catledge; Lara Honos-Webb; Lea Vella; Edwin T Tasch Journal: Arch Gen Psychiatry Date: 2005-09
Authors: K M Scott; R Bruffaerts; A Tsang; J Ormel; J Alonso; M C Angermeyer; C Benjet; E Bromet; G de Girolamo; R de Graaf; I Gasquet; O Gureje; J M Haro; Y He; R C Kessler; D Levinson; Z N Mneimneh; M A Oakley Browne; J Posada-Villa; D J Stein; T Takeshima; M Von Korff Journal: J Affect Disord Date: 2007-02-09 Impact factor: 4.839
Authors: Ronald C Kessler; Patricia Berglund; Olga Demler; Robert Jin; Doreen Koretz; Kathleen R Merikangas; A John Rush; Ellen E Walters; Philip S Wang Journal: JAMA Date: 2003-06-18 Impact factor: 56.272
Authors: A D Sadovnick; R A Remick; J Allen; E Swartz; I M Yee; K Eisen; R Farquhar; S A Hashimoto; J Hooge; L F Kastrukoff; W Morrison; J Nelson; J Oger; D W Paty Journal: Neurology Date: 1996-03 Impact factor: 9.910
Authors: Narineh Hartoonian; Alexandra L Terrill; Meghan L Beier; Aaron P Turner; Melissa A Day; Kevin N Alschuler Journal: Rehabil Psychol Date: 2014-12-15
Authors: Brittany Litster; Kirsten M Fiest; Scott B Patten; John D Fisk; John R Walker; Lesley A Graff; James M Bolton; Jitender Sareen; James J Marriott; Lindsay I Berrigan; Charles N Bernstein; Ryan Zarychanski; Alexander Singer; Carol A Hitchon; Christine A Peschken; Ruth Ann Marrie Journal: Int J MS Care Date: 2016 Nov-Dec