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Literature DB >> 20802797

Efficient Suzuki and Stille Reactions for Regioselective Strategies of Incorporation of the 1,3-Oxazole Heterocycle. Mild Desulfonylation for the Synthesis of C-4 and C-5 Monosubstituted Oxazoles.

Abstract

Suzuki and Stille cross-coupling reactions are surveyed for site-selective C-4 and C-5 elaboration of 2-(phenylsulfonyl)-1,3-oxazole derivatives. Conditions for mild reductive desulfonylations provide for direct incorporation of the intact oxazole heterocycle through bonding at C-4 and C-5.

Entities: Chemical Gene

Year: 2010 PMID： 20802797 PMCID： PMC2927007 DOI： 10.1055/s-0029-1220128

Source DB: PubMed Journal: Synlett ISSN： 0936-5214 Impact factor: 2.454

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References

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Journal: J Nat Prod Date: 2009-04 Impact factor: 4.050

Efficient Suzuki and Stille Reactions for Regioselective Strategies of Incorporation of the 1,3-Oxazole Heterocycle. Mild Desulfonylation for the Synthesis of C-4 and C-5 Monosubstituted Oxazoles.

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