Literature DB >> 20737224

Chondrosis of the disc - risk factor for osteoporotic vertebral fractures (biomechanical analysis).

Jaroslava Wendlová1.   

Abstract

Based on biomechanical analysis, we present an until now unrecognised new view on pathological interactive relations in basic functional motor segments of the spine (vertebra - disc - vertebra), elevating the risk of osteoporotic vertebral fractures. They are classified as follows: 1. Degenerative alterations of intervertebral disc (chondrosis); 1a) decrease of intervertebral disc viscoelasticity; 1b) increase of compressive and tensile stress in the intervertebral disc. Loading the spine increases the compressive and tensile stress in the disc, afflicted by chondrosis, beyond physiological values. This increase conditions the non-physiological elevation of reaction compression forces in adjacent vertebrae, representing a fracture risk for endplates of these vertebrae. 2. Osteoporosis of vertebrae; 2a) decrease of vertebra elasticity and strength; 2b) phenomenon of local elevated compressive stress in the vertebra fracture site. In the vertebral body endplate infraction or fracture site develop a locus minoris of resistance and it contributes to the progression of breaking the vertebra and its whole compression by loading the spine with compressive force. With regard to the fact that above-mentioned risk factors are influenceable, we suggest preventive measures.

Entities:  

Mesh:

Year:  2010        PMID: 20737224     DOI: 10.1007/s10354-010-0823-0

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  11 in total

1.  Degeneration affects the fiber reorientation of human annulus fibrosus under tensile load.

Authors:  Heather Anne L Guerin; Dawn M Elliott
Journal:  J Biomech       Date:  2005-06-13       Impact factor: 2.712

Review 2.  The lumbar degenerative disc: confusion, mechanics, management.

Authors:  Paul Keetae Kim; Charles Leon Branch
Journal:  Clin Neurosurg       Date:  2006

3.  Bone quality. Elasticity and strength.

Authors:  J Wendlova
Journal:  Bratisl Lek Listy       Date:  2008       Impact factor: 1.278

4.  The role of the nucleus pulposus in neutral zone human lumbar intervertebral disc mechanics.

Authors:  Marco Cannella; Amy Arthur; Shanee Allen; Michael Keane; Abhijeet Joshi; Edward Vresilovic; Michele Marcolongo
Journal:  J Biomech       Date:  2008-06-20       Impact factor: 2.712

5.  Internal strains in healthy and degenerated lumbar intervertebral discs.

Authors:  Anthony Tsantrizos; Keita Ito; Max Aebi; Thomas Steffen
Journal:  Spine (Phila Pa 1976)       Date:  2005-10-01       Impact factor: 3.468

6.  Deformation of the vertebral end-plate under axial loading of the spine.

Authors:  P Brinckmann; W Frobin; E Hierholzer; M Horst
Journal:  Spine (Phila Pa 1976)       Date:  1983 Nov-Dec       Impact factor: 3.468

7.  1980 Volvo award in biomechanics. Measurement of the distribution of axial stress on the end-plate of the vertebral body.

Authors:  M Horst; P Brinckmann
Journal:  Spine (Phila Pa 1976)       Date:  1981 May-Jun       Impact factor: 3.468

8.  The dependence of the elastic properties of osteoporotic cancellous bone on volume fraction and fabric.

Authors:  Jasper Homminga; Barbara R Mccreadie; Harrie Weinans; Rik Huiskes
Journal:  J Biomech       Date:  2003-10       Impact factor: 2.712

Review 9.  The structural properties of normal and osteoporotic bone.

Authors:  Thomas A Einhorn
Journal:  Instr Course Lect       Date:  2003

Review 10.  Pathophysiology of the human intervertebral disc.

Authors:  Alessandra Colombini; Giovanni Lombardi; Massimiliano Marco Corsi; Giuseppe Banfi
Journal:  Int J Biochem Cell Biol       Date:  2007-12-28       Impact factor: 5.085

View more
  2 in total

Review 1.  Incomplete burst fractures of the thoracolumbar spine: a review of literature.

Authors:  U J Spiegl; C Josten; B M Devitt; C-E Heyde
Journal:  Eur Spine J       Date:  2017-05-25       Impact factor: 3.134

2.  Shock absorbing function study on denucleated intervertebral disc with or without hydrogel injection through static and dynamic biomechanical tests in vitro.

Authors:  Zhiyu Zhou; Manman Gao; Fuxin Wei; Jiabi Liang; Wenbin Deng; Xuejun Dai; Guangqian Zhou; Xuenong Zou
Journal:  Biomed Res Int       Date:  2014-06-22       Impact factor: 3.411

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.