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Literature DB >> 20715768

Room-temperature aromatization of tetrahydro-β-carbolines by 2-iodoxybenzoic acid: utility in a total synthesis of eudistomin U.

Abstract

2-Iodoxybenzoic acid is a convenient reagent for the dehydrogenation of tetrahydro-β-carbolines to their aromatic forms under mild conditions. The utility of the method was demonstrated in a total synthesis of the marine indole alkaloid eudistomin U.

Entities: Chemical Disease Species

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Year: 2010 PMID： 20715768 PMCID： PMC2937063 DOI： 10.1021/ol101688x

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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