Literature DB >> 20684519

Synthesis and biological evaluation of (+/-)-dinemasone C and analogues.

Amie M Stewart1, Kathrin Meier, Barbara Schulz, Michael Steinert, Barry B Snider.   

Abstract

Dinemasone C was prepared in three steps (8% overall yield) from cis-tetrahydro-4-hydroxy-6-methyl-2-pyrone by aldol reaction with 2,4-hexadienal, epoxidation followed by cyclization, and epimerization of the ring fusion. Dinemasone C, epi-dinemasone C, anhydrodinemasone BC, and nor-dinemasone B are active against bacteria, including Legionella pneumophila Corby, algae, and fungi.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20684519      PMCID： PMC2975019          DOI： 10.1021/jo101408s

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  Waol B, a new trihydrofuran derivative with cytocidal activity, isolated from Myceliophthora lutea.

Authors:  O Nozawa; T Okazaki; S Morimoto; Z X Chen; B M He; K Mizoue
Journal:  J Antibiot (Tokyo)       Date:  2000-11       Impact factor: 2.649

2.  A novel bioactive delta lactone FD-211. Taxonomy, isolation and characterization.

Authors:  O Nozawa; T Okazaki; N Sakai; T Komurasaki; K Hanada; S Morimoto; Z X Chen; B M He; K Mizoue
Journal:  J Antibiot (Tokyo)       Date:  1995-02       Impact factor: 2.649

3.  Synthesis of (-)-TAN-2483A. Revision of the structures and syntheses of (+/-)-FD-211 (waol A) and (+/-)-FD-212 (waol B).

Authors:  Xiaolei Gao; Masakazu Nakadai; Barry B Snider
Journal:  Org Lett       Date:  2003-02-20       Impact factor: 6.005

4.  Allylic alcohol transposition by ortho ester-initiated carbonate extension. synthesis of the vasodilator 11(R),12(S),15(S)-trihydroxyeicosa- 5(Z),8(Z),13(E)-trienoic acid.

Authors:  Raymond E Conrow
Journal:  Org Lett       Date:  2006-05-25       Impact factor: 6.005

5.  Syntheses of (-)-TAN-2483A, (-)-massarilactone B, and the fusidilactone B ring system. Revision of the structures of and syntheses of (+/-)-Waol A (FD-211) and (+/-)-Waol B (FD-212).

Authors:  Xiaolei Gao; Barry B Snider
Journal:  J Org Chem       Date:  2004-08-20       Impact factor: 4.354
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.