Literature DB >> 7706120

A novel bioactive delta lactone FD-211. Taxonomy, isolation and characterization.

O Nozawa1, T Okazaki, N Sakai, T Komurasaki, K Hanada, S Morimoto, Z X Chen, B M He, K Mizoue.   

Abstract

During our screening program for natural product drugs effective against multidrug-resistant mammalian cells, we have discovered a new delta lactone FD-211 from the fermantation broth of Myceliophthora lutea TF-0409. FD-211 had a broad spectrum activity against cultured tumor cell lines, including adriamycin-resistant HL-60 cells.

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Year:  1995        PMID: 7706120     DOI: 10.7164/antibiotics.48.113

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Waol A, trans-dihydrowaol A, and cis-dihydrowaol A: polyketide-derived γ-lactones from a Volutella species.

Authors:  Tamam El-Elimat; Mario Figueroa; Huzefa A Raja; Audrey F Adcock; David J Kroll; Steven M Swanson; Mansukh C Wani; Cedric J Pearce; Nicholas H Oberlies
Journal:  Tetrahedron Lett       Date:  2013-08-07       Impact factor: 2.415

2.  Synthesis and biological evaluation of (+/-)-dinemasone C and analogues.

Authors:  Amie M Stewart; Kathrin Meier; Barbara Schulz; Michael Steinert; Barry B Snider
Journal:  J Org Chem       Date:  2010-09-03       Impact factor: 4.354

  2 in total

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