Literature DB >> 20681948

RING domain dimerization is essential for RNF4 function.

Chu Wai Liew1, Huaiyu Sun, Tony Hunter, Catherine L Day.   

Abstract

RNF4 [RING (really interesting new gene) finger protein 4] family ubiquitin ligases are RING E3 ligases that regulate the homoeostasis of SUMOylated proteins by promoting their ubiquitylation. In the present paper we report that the RING domain of RNF4 forms a stable dimer, and that dimerization is required for ubiquitin transfer. Our results suggest that the stability of the E2~ubiquitin thioester bond is regulated by RING domain dimerization.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20681948      PMCID： PMC3104014          DOI： 10.1042/BJ20100957

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  22 in total

1.  Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation.

Authors:  Jing Song; Ziming Zhang; Weidong Hu; Yuan Chen
Journal:  J Biol Chem       Date:  2005-10-03       Impact factor: 5.157

2.  Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases.

Authors:  Engin Ozkan; Hongtao Yu; Johann Deisenhofer
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-19       Impact factor: 11.205

3.  Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

Authors:  J R Mullen; V Kaliraman; S S Ibrahim; S J Brill
Journal:  Genetics       Date:  2001-01       Impact factor: 4.562

4.  An essential function of the extreme C-terminus of MDM2 can be provided by MDMX.

Authors:  Stjepan Uldrijan; Willem-Jan Pannekoek; Karen H Vousden
Journal:  EMBO J       Date:  2006-12-14       Impact factor: 11.598

5.  Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins.

Authors:  Huaiyu Sun; Joel D Leverson; Tony Hunter
Journal:  EMBO J       Date:  2007-08-30       Impact factor: 11.598

6.  SUMO-targeted ubiquitin ligases in genome stability.

Authors:  John Prudden; Stephanie Pebernard; Grazia Raffa; Daniela A Slavin; J Jefferson P Perry; John A Tainer; Clare H McGowan; Michael N Boddy
Journal:  EMBO J       Date:  2007-08-30       Impact factor: 11.598

7.  E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.

Authors:  Devin E Christensen; Peter S Brzovic; Rachel E Klevit
Journal:  Nat Struct Mol Biol       Date:  2007-09-16       Impact factor: 15.369

Review 8.  Basic methods for fission yeast.

Authors:  Susan L Forsburg; Nicholas Rhind
Journal:  Yeast       Date:  2006-02       Impact factor: 3.239

Review 9.  Choosing and using Schizosaccharomyces pombe plasmids.

Authors:  Rania Siam; William P Dolan; Susan L Forsburg
Journal:  Methods       Date:  2004-07       Impact factor: 3.608

10.  Fission yeast Rnf4 homologs are required for DNA repair.

Authors:  Ana Kosoy; Teresa M Calonge; Emily A Outwin; Matthew J O'Connell
Journal:  J Biol Chem       Date:  2007-05-14       Impact factor: 5.157
View more
  46 in total

Review 1.  HECT and RING finger families of E3 ubiquitin ligases at a glance.

Authors:  Meredith B Metzger; Ventzislava A Hristova; Allan M Weissman
Journal:  J Cell Sci       Date:  2012-02-01       Impact factor: 5.285

2.  Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.

Authors:  Maritza Lienlaf; Fumiaki Hayashi; Francesca Di Nunzio; Naoya Tochio; Takanori Kigawa; Shigeyuki Yokoyama; Felipe Diaz-Griffero
Journal:  J Virol       Date:  2011-07-06       Impact factor: 5.103

3.  Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization.

Authors:  Rebecca Feltham; Bodhi Bettjeman; Rhesa Budhidarmo; Peter D Mace; Sarah Shirley; Stephen M Condon; Srinivas K Chunduru; Mark A McKinlay; David L Vaux; John Silke; Catherine L Day
Journal:  J Biol Chem       Date:  2011-03-10       Impact factor: 5.157

4.  Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation.

Authors:  Yigit Erker; Helene Neyret-Kahn; Jacob S Seeler; Anne Dejean; Azeddine Atfi; Laurence Levy
Journal:  Mol Cell Biol       Date:  2013-03-25       Impact factor: 4.272

5.  The RING-Finger Ubiquitin Ligase HAF1 Mediates Heading date 1 Degradation during Photoperiodic Flowering in Rice.

Authors:  Ying Yang; Debao Fu; Chunmei Zhu; Yizhou He; Huijun Zhang; Tao Liu; Xianghua Li; Changyin Wu
Journal:  Plant Cell       Date:  2015-08-21       Impact factor: 11.277

6.  Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structure.

Authors:  Manjeet Mukherjee; Fan Jing-Song; Sarath Ramachandran; Graeme R Guy; J Sivaraman
Journal:  J Biol Chem       Date:  2014-07-29       Impact factor: 5.157

Review 7.  New insights into ubiquitin E3 ligase mechanism.

Authors:  Christopher E Berndsen; Cynthia Wolberger
Journal:  Nat Struct Mol Biol       Date:  2014-04       Impact factor: 15.369

8.  Trafficking of the transcription factor Nrf2 to promyelocytic leukemia-nuclear bodies: implications for degradation of NRF2 in the nucleus.

Authors:  Melanie Theodore Malloy; Deneshia J McIntosh; Treniqka S Walters; Andrea Flores; J Shawn Goodwin; Ifeanyi J Arinze
Journal:  J Biol Chem       Date:  2013-03-29       Impact factor: 5.157

9.  A single heterologously expressed plant cellulose synthase isoform is sufficient for cellulose microfibril formation in vitro.

Authors:  Pallinti Purushotham; Sung Hyun Cho; Sara M Díaz-Moreno; Manish Kumar; B Tracy Nixon; Vincent Bulone; Jochen Zimmer
Journal:  Proc Natl Acad Sci U S A       Date:  2016-09-19       Impact factor: 11.205

10.  An arginine-rich motif of ring finger protein 4 (RNF4) oversees the recruitment and degradation of the phosphorylated and SUMOylated Krüppel-associated box domain-associated protein 1 (KAP1)/TRIM28 protein during genotoxic stress.

Authors:  Ching-Ying Kuo; Xu Li; Xiang-Qian Kong; Cheng Luo; Che-Chang Chang; Yiyin Chung; Hsiu-Ming Shih; Keqin Kathy Li; David K Ann
Journal:  J Biol Chem       Date:  2014-06-06       Impact factor: 5.157
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.