Literature DB >> 20675764

The effect of injections of botulinum toxin type A combined with casting on the equinus gait of children with cerebral palsy.

S Hayek1, A Gershon, S Wientroub, Z Yizhar.   

Abstract

Our aim was to evaluate the effect of adding inhibitory casting to the treatment of young children with cerebral palsy who received injections of botulinum neurotoxin A (BoNT-A) to gastrocnemius for equinus gait. Of the 20 patients in the series, 11 in group A had inhibitory casts applied on the day of the first set of BoNT-A injections and nine in group B did not have casting. Both groups received another BoNT-A injection four months later. The patients were followed for eight months and examined at five intervals. Both groups showed significant improvement in gait parameters and function (p < 0.0001) and selective motor control (p = 0.041, - 0.036) throughout the study. Group A had significantly better passive dorsiflexion of the ankle (p = 0.029), observational gait score (p = 0.006) and selective motor control (p = 0.036). We conclude that the addition of inhibitory casting enhances and prolongs the results of treatment and mainly influences the passive range of movement, while BoNT-A mostly influences the dynamic motion. The second injection further improved the results of most parameters. The gross motor function measure, the selective motor control test and the modified Tardieu scale correlated well with the results of treatment. We recommend the use of inhibitory casting whenever augmentation of the effect of treatment with BoNT-A is needed.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20675764     DOI: 10.1302/0301-620X.92B8.23086

Source DB:  PubMed          Journal:  J Bone Joint Surg Br        ISSN: 0301-620X


  9 in total

Review 1.  Relationship between ankle function and walking ability for children and young adults with cerebral palsy: A systematic review of deficits and targeted interventions.

Authors:  Benjamin C Conner; Nushka M Remec; Cassidy M Michaels; Chase W Wallace; Emily Andrisevic; Zachary F Lerner
Journal:  Gait Posture       Date:  2021-10-25       Impact factor: 2.840

2.  The efficacy of neuroprosthesis in young hemiplegic patients, measured by three different gait indices: early results.

Authors:  Barry Danino; Sam Khamis; Yoram Hemo; Reuven Batt; Erel Snir; Shlomo Wientroub; Shlomo Hayek
Journal:  J Child Orthop       Date:  2013-11-08       Impact factor: 1.548

3.  The influence of botulinum toxin A injections into the calf muscles on genu recurvatum in children with cerebral palsy.

Authors:  Matthias C M Klotz; Sebastian I Wolf; Daniel Heitzmann; Simone Gantz; Frank Braatz; Thomas Dreher
Journal:  Clin Orthop Relat Res       Date:  2013-03-06       Impact factor: 4.176

Review 4.  Stretch for the treatment and prevention of contractures.

Authors:  Lisa A Harvey; Owen M Katalinic; Robert D Herbert; Anne M Moseley; Natasha A Lannin; Karl Schurr
Journal:  Cochrane Database Syst Rev       Date:  2017-01-09

Review 5.  Best clinical practice in botulinum toxin treatment for children with cerebral palsy.

Authors:  Walter Strobl; Tim Theologis; Reinald Brunner; Serdar Kocer; Elke Viehweger; Ignacio Pascual-Pascual; Richard Placzek
Journal:  Toxins (Basel)       Date:  2015-05-11       Impact factor: 4.546

6.  Multiple testing in orthopedic literature: a common problem?

Authors:  Monique M J Walenkamp; Kit C B Roes; Mohit Bhandari; J Carel Goslings; Niels W L Schep
Journal:  BMC Res Notes       Date:  2013-09-21

7.  The effects of botulinum toxin type A on improvement and dynamic spastic equinus correction in children with cerebral palsy - preliminary results.

Authors:  Hristina Colovic; Lidija Dimitrijevic; Ivona Stankovic; Dejan Nikolic; Dragana Radovic-Janosevic; Dragoljub Zivanovic
Journal:  Arch Med Sci       Date:  2014-10-23       Impact factor: 3.318

8.  Efficacy of conservative treatment for spastic cerebral palsy children with equinus gait: a systematic review and meta-analysis.

Authors:  Krongkaew Klaewkasikum; Tanyaporn Patathong; Patarawan Woratanarat; Thira Woratanarat; Kunlawat Thadanipon; Sasivimol Rattanasiri; Ammarin Thakkinstian
Journal:  J Orthop Surg Res       Date:  2022-09-08       Impact factor: 2.677

Review 9.  Botulinum Toxin Induced Atrophy: An Uncharted Territory.

Authors:  Mehri Salari; Soumya Sharma; Mandar S Jog
Journal:  Toxins (Basel)       Date:  2018-08-02       Impact factor: 4.546

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.