Literature DB >> 20664203

Long-term vacuum-assisted closure in open abdomen due to secondary peritonitis: a retrospective evaluation of a selected group of patients.

Moritz Schmelzle1, Ingo Alldinger, Hanno Matthaei, Feride Aydin, Ingo Wallert, Claus F Eisenberger, Jan Schulte Am Esch, Levent Dizdar, Stefan A Topp, Qin Yang, Wolfram T Knoefel.   

Abstract

BACKGROUND/AIMS: Vacuum-assisted closure (VAC) leads to a high fascial closure rate in open abdomen within the first week of treatment. However, little data exist on the role of long-term VAC treatment in patients with peritonitis, where fascial closure cannot be accomplished within the first days.
METHODS: We reviewed the medical records of 49 patients with open abdomen for more than 7 days due to secondary peritonitis, who underwent a VAC-treatment. Nonparametric analysis was performed using chi(2) test or Fisher's exact test.
RESULTS: Fascial closure could be accomplished in only 11 patients (22%), whereas complications occurred in 43 patients (88%). Re-explorations after starting VAC were associated with the occurrence of enterocutaneous fistula (p < 0.001) and were also of prognostic value regarding the rate of fascial closure (p = 0.033).
CONCLUSIONS: If fascial closure cannot be accomplished within the first days, patients show a dramatically lower fascial closure and an increased complication rate with VAC. Further studies are needed to evaluate whether this subgroup really benefits from VAC. Copyright 2010 S. Karger AG, Basel.

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Mesh:

Year:  2010        PMID: 20664203     DOI: 10.1159/000314609

Source DB:  PubMed          Journal:  Dig Surg        ISSN: 0253-4886            Impact factor:   2.588


  15 in total

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Review 4.  Systematic review and meta-analysis of the open abdomen and temporary abdominal closure techniques in non-trauma patients.

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Review 10.  Current status of the open abdomen treatment for intra-abdominal infection.

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Journal:  Gastroenterol Res Pract       Date:  2013-10-02       Impact factor: 2.260

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