Literature DB >> 20659507

Certainties, doubts and hypotheses in porcine reproductive and respiratory syndrome virus immunobiology.

Laila Darwich1, Ivan Díaz, Enric Mateu.   

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most costly pathogens for the swine industry. Since its emergence some 20 years ago, much has been learned about the immunobiology of PRRSV. Although vaccines are available, they do not provide full and universal protection against PRRSV infection. In the present review, current knowledge on the virus's immunobiology will be discussed including: role of viral receptors, innate immune response to the virus, regulation of the immune response by PRRSV, and the characteristics and role of adaptive immunity. In addition, some hypotheses for future research in this area are presented.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 20659507     DOI： 10.1016/j.virusres.2010.07.017

Source DB:  PubMed          Journal:  Virus Res        ISSN： 0168-1702            Impact factor:   3.303


  57 in total

1.  Porcine reproductive and respiratory syndrome virus neutralizing antibodies provide in vivo cross-protection to PRRSV1 and PRRSV2 viral challenge.

Authors:  Sally R Robinson; Michael C Rahe; Diem K Gray; Kyra V Martins; Michael P Murtaugh
Journal:  Virus Res       Date:  2018-02-03       Impact factor: 3.303

Review 2.  Porcine reproductive and respiratory syndrome virus vaccines: Immunogenicity, efficacy and safety aspects.

Authors:  Wasin Charerntantanakul
Journal:  World J Virol       Date:  2012-02-12

3.  Reconciling individual and population levels of porcine reproductive and respiratory syndrome virus evolution.

Authors:  Giovanni Franzo; Claudia Maria Tucciarone; Mattia Cecchinato; Michele Drigo
Journal:  Virol Sin       Date:  2017-08       Impact factor: 4.327

4.  The activation of the IFNβ induction/signaling pathway in porcine alveolar macrophages by porcine reproductive and respiratory syndrome virus is variable.

Authors:  Christopher C Overend; Junru Cui; Marvin J Grubman; Antonio E Garmendia
Journal:  Vet Res Commun       Date:  2016-11-28       Impact factor: 2.459

5.  A single amino acid deletion in the matrix protein of porcine reproductive and respiratory syndrome virus confers resistance to a polyclonal swine antibody with broadly neutralizing activity.

Authors:  Benjamin R Trible; Luca N Popescu; Nicholas Monday; Jay G Calvert; Raymond R R Rowland
Journal:  J Virol       Date:  2015-04-08       Impact factor: 5.103

6.  Carbon Monoxide Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by the Cyclic GMP/Protein Kinase G and NF-κB Signaling Pathway.

Authors:  Angke Zhang; Lijuan Zhao; Na Li; Hong Duan; Hongliang Liu; Fengxing Pu; Gaiping Zhang; En-Min Zhou; Shuqi Xiao
Journal:  J Virol       Date:  2016-12-16       Impact factor: 5.103

7.  Knockdown expression of IL-10Rα gene inhibits PRRSV replication and elevates immune responses in PBMCs of Tibetan pig in vitro.

Authors:  Yihui Chen; Ye Wang; Kai Zeng; Yun-Feng Lei; Xiao-Hui Chen; San-Cheng Ying; Xue-Bin Lv; Zezhou Wang; Rong Gao
Journal:  Vet Res Commun       Date:  2017-12-08       Impact factor: 2.459

8.  Arterivirus minor envelope proteins are a major determinant of viral tropism in cell culture.

Authors:  Debin Tian; Zuzhang Wei; Jessika C Zevenhoven-Dobbe; Runxia Liu; Guangzhi Tong; Eric J Snijder; Shishan Yuan
Journal:  J Virol       Date:  2012-01-18       Impact factor: 5.103

9.  Genetic relationships of antibody response, viremia level, and weight gain in pigs experimentally infected with porcine reproductive and respiratory syndrome virus1.

Authors:  Andrew S Hess; Ben R Trible; Melanie K Hess; Raymond R Rowland; Joan K Lunney; Graham S Plastow; Jack C M Dekkers
Journal:  J Anim Sci       Date:  2018-09-07       Impact factor: 3.159

10.  Antiviral regulation in porcine monocytic cells at different activation states.

Authors:  Yongming Sang; Raymond R R Rowland; Frank Blecha
Journal:  J Virol       Date:  2014-07-23       Impact factor: 5.103
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