Literature DB >> 20646918

Semantic relations for problem-oriented medical records.

Ozlem Uzuner1, Jonathan Mailoa, Russell Ryan, Tawanda Sibanda.   

Abstract

OBJECTIVE: We describe semantic relation (SR) classification on medical discharge summaries. We focus on relations targeted to the creation of problem-oriented records. Thus, we define relations that involve the medical problems of patients. METHODS AND MATERIALS: We represent patients' medical problems with their diseases and symptoms. We study the relations of patients' problems with each other and with concepts that are identified as tests and treatments. We present an SR classifier that studies a corpus of patient records one sentence at a time. For all pairs of concepts that appear in a sentence, this SR classifier determines the relations between them. In doing so, the SR classifier takes advantage of surface, lexical, and syntactic features and uses these features as input to a support vector machine. We apply our SR classifier to two sets of medical discharge summaries, one obtained from the Beth Israel-Deaconess Medical Center (BIDMC), Boston, MA and the other from Partners Healthcare, Boston, MA.
RESULTS: On the BIDMC corpus, our SR classifier achieves micro-averaged F-measures that range from 74% to 95% on the various relation types. On the Partners corpus, the micro-averaged F-measures on the various relation types range from 68% to 91%. Our experiments show that lexical features (in particular, tokens that occur between candidate concepts, which we refer to as inter-concept tokens) are very informative for relation classification in medical discharge summaries. Using only the inter-concept tokens in the corpus, our SR classifier can recognize 84% of the relations in the BIDMC corpus and 72% of the relations in the Partners corpus.
CONCLUSION: These results are promising for semantic indexing of medical records. They imply that we can take advantage of lexical patterns in discharge summaries for relation classification at a sentence level.
Copyright © 2010 Elsevier B.V. All rights reserved.

Entities:  

Mesh:

Year:  2010        PMID: 20646918      PMCID: PMC2948592          DOI: 10.1016/j.artmed.2010.05.006

Source DB:  PubMed          Journal:  Artif Intell Med        ISSN: 0933-3657            Impact factor:   5.326


  16 in total

1.  Argument identification for arterial branching predications asserted in cardiac catheterization reports.

Authors:  T C Rindflesch; C A Bean; C A Sneiderman
Journal:  Proc AMIA Symp       Date:  2000

2.  Exploring text mining from MEDLINE.

Authors:  Padmini Srinivasan; Thomas Rindflesch
Journal:  Proc AMIA Symp       Date:  2002

3.  Adding a medical lexicon to an English Parser.

Authors:  Peter Szolovits
Journal:  AMIA Annu Symp Proc       Date:  2003

4.  Extracting phenotypic information from the literature via natural language processing.

Authors:  Lifeng Chen; Carol Friedman
Journal:  Stud Health Technol Inform       Date:  2004

5.  Agreement, the f-measure, and reliability in information retrieval.

Authors:  George Hripcsak; Adam S Rothschild
Journal:  J Am Med Inform Assoc       Date:  2005-01-31       Impact factor: 4.497

6.  Automation of a problem list using natural language processing.

Authors:  Stephane Meystre; Peter J Haug
Journal:  BMC Med Inform Decis Mak       Date:  2005-08-31       Impact factor: 2.796

7.  Indexing UMLS Semantic Types for Medical Question-Answering.

Authors:  Thierry Delbecque; Pierre Jacquemart; Pierre Zweigenbaum
Journal:  Stud Health Technol Inform       Date:  2005

8.  Extracting causal relations on HIV drug resistance from literature.

Authors:  Quoc-Chinh Bui; Breanndán O Nualláin; Charles A Boucher; Peter M A Sloot
Journal:  BMC Bioinformatics       Date:  2010-02-23       Impact factor: 3.169

9.  Medical records that guide and teach.

Authors:  L L Weed
Journal:  N Engl J Med       Date:  1968-03-21       Impact factor: 91.245

10.  A general natural-language text processor for clinical radiology.

Authors:  C Friedman; P O Alderson; J H Austin; J J Cimino; S B Johnson
Journal:  J Am Med Inform Assoc       Date:  1994 Mar-Apr       Impact factor: 4.497

View more
  10 in total

1.  Using domain knowledge and domain-inspired discourse model for coreference resolution for clinical narratives.

Authors:  Prateek Jindal; Dan Roth
Journal:  J Am Med Inform Assoc       Date:  2012-07-10       Impact factor: 4.497

2.  2010 i2b2/VA challenge on concepts, assertions, and relations in clinical text.

Authors:  Özlem Uzuner; Brett R South; Shuying Shen; Scott L DuVall
Journal:  J Am Med Inform Assoc       Date:  2011-06-16       Impact factor: 4.497

3.  Learning to identify treatment relations in clinical text.

Authors:  Cosmin A Bejan; Joshua C Denny
Journal:  AMIA Annu Symp Proc       Date:  2014-11-14

4.  Classifying relations in clinical narratives using segment graph convolutional and recurrent neural networks (Seg-GCRNs).

Authors:  Yifu Li; Ran Jin; Yuan Luo
Journal:  J Am Med Inform Assoc       Date:  2019-03-01       Impact factor: 4.497

5.  Automatic approach for constructing a knowledge graph of knee osteoarthritis in Chinese.

Authors:  Xin Li; Haoyang Liu; Xu Zhao; Guigang Zhang; Chunxiao Xing
Journal:  Health Inf Sci Syst       Date:  2020-02-27

6.  Segment convolutional neural networks (Seg-CNNs) for classifying relations in clinical notes.

Authors:  Yuan Luo; Yu Cheng; Özlem Uzuner; Peter Szolovits; Justin Starren
Journal:  J Am Med Inform Assoc       Date:  2018-01-01       Impact factor: 4.497

7.  Learning Inter-Sentence, Disorder-Centric, Biomedical Relationships from Medical Literature.

Authors:  Anton H van der Vegt; Guido Zuccon; Bevan Koopman
Journal:  AMIA Annu Symp Proc       Date:  2020-03-04

8.  Automatic lymphoma classification with sentence subgraph mining from pathology reports.

Authors:  Yuan Luo; Aliyah R Sohani; Ephraim P Hochberg; Peter Szolovits
Journal:  J Am Med Inform Assoc       Date:  2014-01-15       Impact factor: 4.497

9.  A context-blocks model for identifying clinical relationships in patient records.

Authors:  Rezarta Islamaj Doğan; Aurélie Névéol; Zhiyong Lu
Journal:  BMC Bioinformatics       Date:  2011-06-09       Impact factor: 3.169

10.  Normalizing acronyms and abbreviations to aid patient understanding of clinical texts: ShARe/CLEF eHealth Challenge 2013, Task 2.

Authors:  Danielle L Mowery; Brett R South; Lee Christensen; Jianwei Leng; Laura-Maria Peltonen; Sanna Salanterä; Hanna Suominen; David Martinez; Sumithra Velupillai; Noémie Elhadad; Guergana Savova; Sameer Pradhan; Wendy W Chapman
Journal:  J Biomed Semantics       Date:  2016-07-01
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.