Literature DB >> 22781192

Using domain knowledge and domain-inspired discourse model for coreference resolution for clinical narratives.

Prateek Jindal1, Dan Roth.   

Abstract

OBJECTIVE: This paper presents a coreference resolution system for clinical narratives. Coreference resolution aims at clustering all mentions in a single document to coherent entities.
MATERIALS AND METHODS: A knowledge-intensive approach for coreference resolution is employed. The domain knowledge used includes several domain-specific lists, a knowledge intensive mention parsing, and task informed discourse model. Mention parsing allows us to abstract over the surface form of the mention and represent each mention using a higher-level representation, which we call the mention's semantic representation (SR). SR reduces the mention to a standard form and hence provides better support for comparing and matching. Existing coreference resolution systems tend to ignore discourse aspects and rely heavily on lexical and structural cues in the text. The authors break from this tradition and present a discourse model for "person" type mentions in clinical narratives, which greatly simplifies the coreference resolution.
RESULTS: This system was evaluated on four different datasets which were made available in the 2011 i2b2/VA coreference challenge. The unweighted average of F1 scores (over B-cubed, MUC and CEAF) varied from 84.2% to 88.1%. These experiments show that domain knowledge is effective for different mention types for all the datasets. DISCUSSION: Error analysis shows that most of the recall errors made by the system can be handled by further addition of domain knowledge. The precision errors, on the other hand, are more subtle and indicate the need to understand the relations in which mentions participate for building a robust coreference system.
CONCLUSION: This paper presents an approach that makes an extensive use of domain knowledge to significantly improve coreference resolution. The authors state that their system and the knowledge sources developed will be made publicly available.

Entities:  

Mesh:

Year:  2012        PMID: 22781192      PMCID: PMC3638172          DOI: 10.1136/amiajnl-2011-000767

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  7 in total

Review 1.  Evaluating the state of the art in coreference resolution for electronic medical records.

Authors:  Ozlem Uzuner; Andreea Bodnari; Shuying Shen; Tyler Forbush; John Pestian; Brett R South
Journal:  J Am Med Inform Assoc       Date:  2012-02-24       Impact factor: 4.497

2.  MCORES: a system for noun phrase coreference resolution for clinical records.

Authors:  Andreea Bodnari; Peter Szolovits; Özlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2012-03-14       Impact factor: 4.497

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Journal:  J Am Med Inform Assoc       Date:  2010 Sep-Oct       Impact factor: 4.497

4.  Semantic relations for problem-oriented medical records.

Authors:  Ozlem Uzuner; Jonathan Mailoa; Russell Ryan; Tawanda Sibanda
Journal:  Artif Intell Med       Date:  2010-06-19       Impact factor: 5.326

5.  An overview of MetaMap: historical perspective and recent advances.

Authors:  Alan R Aronson; François-Michel Lang
Journal:  J Am Med Inform Assoc       Date:  2010 May-Jun       Impact factor: 4.497

6.  2010 i2b2/VA challenge on concepts, assertions, and relations in clinical text.

Authors:  Özlem Uzuner; Brett R South; Shuying Shen; Scott L DuVall
Journal:  J Am Med Inform Assoc       Date:  2011-06-16       Impact factor: 4.497

7.  Synonym set extraction from the biomedical literature by lexical pattern discovery.

Authors:  John McCrae; Nigel Collier
Journal:  BMC Bioinformatics       Date:  2008-03-24       Impact factor: 3.169

  7 in total
  5 in total

Review 1.  Recent Advances in Clinical Natural Language Processing in Support of Semantic Analysis.

Authors:  S Velupillai; D Mowery; B R South; M Kvist; H Dalianis
Journal:  Yearb Med Inform       Date:  2015-08-13

Review 2.  "Big data" and the electronic health record.

Authors:  M K Ross; W Wei; L Ohno-Machado
Journal:  Yearb Med Inform       Date:  2014-08-15

3.  Document Sublanguage Clustering to Detect Medical Specialty in Cross-institutional Clinical Texts.

Authors:  Kristina Doing-Harris; Olga Patterson; Sean Igo; John Hurdle
Journal:  Proc ACM Int Workshop Data Text Min Biomed Inform       Date:  2013 Oct-Nov

4.  Mission and Sustainability of Informatics for Integrating Biology and the Bedside (i2b2).

Authors:  Shawn Murphy; Adam Wilcox
Journal:  EGEMS (Wash DC)       Date:  2014-09-11

5.  Collecting specialty-related medical terms: Development and evaluation of a resource for Spanish.

Authors:  Pilar López-Úbeda; Alexandra Pomares-Quimbaya; Manuel Carlos Díaz-Galiano; Stefan Schulz
Journal:  BMC Med Inform Decis Mak       Date:  2021-05-04       Impact factor: 2.796

  5 in total

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