Literature DB >> 20633362

Structure and function of G protein-coupled receptors using NMR spectroscopy.

Joseph A Goncalves1, Shivani Ahuja, Sina Erfani, Markus Eilers, Steven O Smith.   

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Year:  2010        PMID： 20633362      PMCID： PMC2907352          DOI： 10.1016/j.pnmrs.2010.04.004

Source DB:  PubMed          Journal:  Prog Nucl Magn Reson Spectrosc        ISSN： 0079-6565            Impact factor:   9.795


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  210 in total

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4.  Transducin-dependent protonation of glutamic acid 134 in rhodopsin.

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5.  Solution NMR spectroscopy of [alpha -15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence.

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6.  Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints.

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7.  A role for direct interactions in the modulation of rhodopsin by omega-3 polyunsaturated lipids.

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8.  The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.

Authors:  Robert Fredriksson; Malin C Lagerström; Lars-Gustav Lundin; Helgi B Schiöth
Journal:  Mol Pharmacol       Date:  2003-06       Impact factor: 4.436

9.  NMR constraints on the location of the retinal chromophore in rhodopsin and bathorhodopsin.

Authors:  M Han; S O Smith
Journal:  Biochemistry       Date:  1995-01-31       Impact factor: 3.162

Review 10.  The Frizzled family: receptors for multiple signal transduction pathways.

Authors:  Hui-Chuan Huang; Peter S Klein
Journal:  Genome Biol       Date:  2004-06-14       Impact factor: 13.583
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1.  Fast NMR data acquisition from bicelles containing a membrane-associated peptide at natural-abundance.

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2.  Uniform isotope labeling of a eukaryotic seven-transmembrane helical protein in yeast enables high-resolution solid-state NMR studies in the lipid environment.

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3.  Site-specific solid-state NMR detection of hydrogen-deuterium exchange reveals conformational changes in a 7-helical transmembrane protein.

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4.  The dynamics of the G protein-coupled neuropeptide Y2 receptor in monounsaturated membranes investigated by solid-state NMR spectroscopy.

Authors:  Lars Thomas; Julian Kahr; Peter Schmidt; Ulrike Krug; Holger A Scheidt; Daniel Huster
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5.  Functional roles of T3.37 and S5.46 in the activation mechanism of the dopamine D1 receptor.

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6.  Characterizing proteins in a native bacterial environment using solid-state NMR spectroscopy.

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7.  Quantum mechanical theory of dynamic nuclear polarization in solid dielectrics.

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8.  Mechanically, magnetically, and "rotationally aligned" membrane proteins in phospholipid bilayers give equivalent angular constraints for NMR structure determination.

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9.  Yeast-expressed human membrane protein aquaporin-1 yields excellent resolution of solid-state MAS NMR spectra.

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10.  Structural transitions of transmembrane helix 6 in the formation of metarhodopsin I.

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