Literature DB >> 20626739

Computational characterization of flow and hemolytic performance of the UltraMag blood pump for circulatory support.

M Ertan Taskin1, Katharine H Fraser, Tao Zhang, Barry Gellman, Andi Fleischli, Kurt A Dasse, Bartley P Griffith, Zhongjun J Wu.   

Abstract

The Levitronix UltraMag blood pump is a next generation, magnetically suspended centrifugal pump and is designed to provide circulatory support for pediatric and adult patients. The aim of this study is to investigate the hemodynamic and hemolytic characteristics of this pump using the computational fluid dynamics (CFD) approach. The computational domain for CFD analysis was constructed from the three-dimensional geometry (3D) of the UltraMag blood pump and meshed into 3D tetrahedral/hybrid elements. The governing equations of fluid flow were computationally solved to obtain a blood flow through the blood pump. Further, hemolytic blood damage was calculated by solving a scalar transport equation where the scalar variable and the source term were obtained utilizing an empirical power-law correlation between the fluid dynamic variables and hemolysis. To obtain mesh independent flow solution, a comparative examination of vector fields, hydrodynamic performance, and hemolysis predictions were carried out. Different sizes of tetrahedral and tetrahedral/hexahedral mixed hybrid models were considered. The mesh independent solutions were obtained by a hybrid model. Laminar and SST κ-ω turbulence flow models were used for different operating conditions. In order to pinpoint the most significant hemolytic region, the flow field analysis was coupled to the hemolysis predictions. In summary, computational characterization of the device was satisfactorily carried out within the targeted operating conditions of the device, and it was observed that the UltraMag blood pump can be safely operated for its intended use to create a circulatory support for both pediatric and adult-sized patients.
© 2010, Copyright the Authors. Artificial Organs © 2010, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

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Year:  2010        PMID: 20626739     DOI: 10.1111/j.1525-1594.2010.01017.x

Source DB:  PubMed          Journal:  Artif Organs        ISSN: 0160-564X            Impact factor:   3.094


  13 in total

Review 1.  The use of computational fluid dynamics in the development of ventricular assist devices.

Authors:  Katharine H Fraser; M Ertan Taskin; Bartley P Griffith; Zhongjun J Wu
Journal:  Med Eng Phys       Date:  2010-11-13       Impact factor: 2.242

2.  Large Eddy Simulation of FDA's Idealized Medical Device.

Authors:  Yann T Delorme; Kameswararao Anupindi; Steven H Frankel
Journal:  Cardiovasc Eng Technol       Date:  2013-12-01       Impact factor: 2.495

3.  A novel wearable pump-lung device: in vitro and acute in vivo study.

Authors:  Tao Zhang; Xufeng Wei; Giacomo Bianchi; Philip M Wong; Brian Biancucci; Bartley P Griffith; Zhongjun J Wu
Journal:  J Heart Lung Transplant       Date:  2011-10-20       Impact factor: 10.247

4.  Proposal of hemodynamically improved design of an axial flow blood pump for LVAD.

Authors:  Vikas Kannojiya; Arup Kumar Das; Prasanta Kumar Das
Journal:  Med Biol Eng Comput       Date:  2019-12-19       Impact factor: 2.602

5.  A quantitative comparison of mechanical blood damage parameters in rotary ventricular assist devices: shear stress, exposure time and hemolysis index.

Authors:  Katharine H Fraser; Tao Zhang; M Ertan Taskin; Bartley P Griffith; Zhongjun J Wu
Journal:  J Biomech Eng       Date:  2012-08       Impact factor: 2.097

6.  Multiblock High Order Large Eddy Simulation of Powered Fontan Hemodynamics: Towards Computational Surgery.

Authors:  Yann T Delorme; Mark D Rodefeld; Steven H Frankel
Journal:  Comput Fluids       Date:  2016-11-09       Impact factor: 3.013

7.  Comparison and experimental validation of fluid dynamic numerical models for a clinical ventricular assist device.

Authors:  Jiafeng Zhang; Pei Zhang; Katharine H Fraser; Bartley P Griffith; Zhongjun J Wu
Journal:  Artif Organs       Date:  2013-02-27       Impact factor: 3.094

8.  Computational modeling of the Food and Drug Administration's benchmark centrifugal blood pump.

Authors:  Bryan C Good; Keefe B Manning
Journal:  Artif Organs       Date:  2020-02-16       Impact factor: 3.094

9.  Computational Fluid Dynamics and Experimental Characterization of the Pediatric Pump-Lung.

Authors:  Zhongjun J Wu; Barry Gellman; Tao Zhang; M Ertan Taskin; Kurt A Dasse; Bartley P Griffith
Journal:  Cardiovasc Eng Technol       Date:  2011-12-01       Impact factor: 2.495

10.  Computational Parametric Study of the Axial and Radial Clearances in a Centrifugal Rotary Blood Pump.

Authors:  Mohammad Amin Rezaienia; Gordon Paul; Eldad Avital; Martin Rothman; Theodosios Korakianitis
Journal:  ASAIO J       Date:  2018 Sep/Oct       Impact factor: 2.872

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