Literature DB >> 20596274

Emergence of Klebsiella pneumoniae carrying bla(VIM) and bla(KPC) genes.

G Meletis1, E Tzampaz, E Protonotariou, D Sofianou.   

Abstract

A Klebsiella pneumoniae clinical isolate resistant to imipenem was recovered from a wound sample. The patient, a 57-year-old man, underwent a surgical resection of small bowel and sigmoid colon and was treated with multiple courses of antimicrobials. PCR analysis revealed that the clinical isolate was carrying simultaneously bla(VIM-1), bla(KPC-2), bla(SHV) and bla(TEM) genes. The concomitant presence of these genes is alarming and poses therapeutic as well as infection control problems.

Entities:  

Keywords:  KPC-2; Klebsiella pneumoniae; SHV; TEM; VIM-1; carbapenemases; β-lactamases

Year:  2010        PMID： 20596274      PMCID： PMC2895282     

Source DB:  PubMed          Journal:  Hippokratia        ISSN： 1108-4189            Impact factor:   0.471


  6 in total

1.  Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece.

Authors:  Gaelle Cuzon; Thierry Naas; Marie Claude Demachy; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2007-12-03       Impact factor: 5.191

2.  Emerging Klebsiella pneumoniae isolates coproducing KPC-2 and VIM-1 carbapenemases.

Authors:  Panagiota Giakkoupi; Olga Pappa; Michalis Polemis; Alkiviadis C Vatopoulos; Vivi Miriagou; Anastasia Zioga; Costas C Papagiannitsis; Leonidas S Tzouvelekis
Journal:  Antimicrob Agents Chemother       Date:  2009-07-06       Impact factor: 5.191

3.  Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae isolates in the clinical laboratory.

Authors:  Athanassios Tsakris; Ioulia Kristo; Aggeliki Poulou; Katerina Themeli-Digalaki; Alexandros Ikonomidis; Dimitra Petropoulou; Spyros Pournaras; Danai Sofianou
Journal:  J Clin Microbiol       Date:  2008-12-10       Impact factor: 5.948

Review 4.  The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria.

Authors:  Patrice Nordmann; Gaelle Cuzon; Thierry Naas
Journal:  Lancet Infect Dis       Date:  2009-04       Impact factor: 25.071

5.  Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae.

Authors:  K F Anderson; D R Lonsway; J K Rasheed; J Biddle; B Jensen; L K McDougal; R B Carey; A Thompson; S Stocker; B Limbago; J B Patel
Journal:  J Clin Microbiol       Date:  2007-06-20       Impact factor: 5.948

6.  Clonal spread of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains in Greece.

Authors:  Spyros Pournaras; Efthimia Protonotariou; Evangelia Voulgari; Ioulia Kristo; Evangelia Dimitroulia; Danai Vitti; Maria Tsalidou; Antonios N Maniatis; Athanassios Tsakris; Danai Sofianou
Journal:  J Antimicrob Chemother       Date:  2009-06-13       Impact factor: 5.790
  6 in total
  8 in total

1.  Coproduction of KPC-18 and VIM-1 Carbapenemases by Enterobacter cloacae: Implications for Newer β-Lactam-β-Lactamase Inhibitor Combinations.

Authors:  Gina K Thomson; James W Snyder; Christi L McElheny; Kenneth S Thomson; Yohei Doi
Journal:  J Clin Microbiol       Date:  2015-12-30       Impact factor: 5.948

2.  Characterization of a novel Klebsiella pneumoniae sequence type 476 carrying both bla KPC-2 and bla IMP-4.

Authors:  Y Wang; W Cao; X Zhu; Z Chen; L Li; B Zhang; B Wang; L Tian; F Wang; C Liu; Z Sun
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-01-21       Impact factor: 3.267

Review 3.  Double- and multi-carbapenemase-producers: the excessively armored bacilli of the current decade.

Authors:  G Meletis; D Chatzidimitriou; N Malisiovas
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-04-18       Impact factor: 3.267

4.  Emergence of Klebsiella pneumoniae Coharboring KPC and VIM Carbapenemases in Colombia.

Authors:  L J Rojas; M F Mojica; V M Blanco; A Correa; M C Montealegre; E De La Cadena; J J Maya; R D Camargo; J P Quinn; M V Villegas
Journal:  Antimicrob Agents Chemother       Date:  2012-12-10       Impact factor: 5.191

5.  First report of a Pseudomonas aeruginosa isolate coharboring KPC and VIM carbapenemases.

Authors:  A Correa; M C Montealegre; M F Mojica; J J Maya; L J Rojas; E P De La Cadena; S J Ruiz; M Recalde; F Rosso; J P Quinn; M V Villegas
Journal:  Antimicrob Agents Chemother       Date:  2012-07-23       Impact factor: 5.191

6.  Detection of New Delhi Metallo-Beta-Lactamase-1 (NDM-1) in carbapenem- resistant Klebsiella pneumoniae isolated from a university hospital in Iran.

Authors:  H Fazeli; M Norouzi-Barough; A M Ahadi; D Shokri; H Solgi
Journal:  Hippokratia       Date:  2015 Jul-Sep       Impact factor: 0.471

7.  Accumulation of carbapenem resistance mechanisms in VIM-2-producing Pseudomonas aeruginosa under selective pressure.

Authors:  G Meletis; N Vavatsi; M Exindari; E Protonotariou; E Sianou; C Haitoglou; D Sofianou; S Pournaras; E Diza
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-09-06       Impact factor: 3.267

8.  A cluster of KPC-2 and VIM-2-producing Klebsiella pneumoniae ST833 isolates from the pediatric service of a Venezuelan Hospital.

Authors:  Aura Falco; Yusibeska Ramos; Esther Franco; Alegría Guzmán; Howard Takiff
Journal:  BMC Infect Dis       Date:  2016-10-22       Impact factor: 3.090
  8 in total

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