| Literature DB >> 17581941 |
K F Anderson1, D R Lonsway, J K Rasheed, J Biddle, B Jensen, L K McDougal, R B Carey, A Thompson, S Stocker, B Limbago, J B Patel.
Abstract
The Klebsiella pneumoniae carbapenem (KPC) beta-lactamase occurs in Enterobacteriaceae and can confer resistance to all beta-lactam agents including carbapenems. The enzyme may confer low-level carbapenem resistance, and the failure of susceptibility methods to identify this resistance has been reported. Automated and nonautomated methods for carbapenem susceptibility were evaluated for identification of KPC-mediated resistance. Ertapenem was a more sensitive indicator of KPC resistance than meropenem and imipenem independently of the method used. Carbapenemase production could be confirmed with the modified Hodge test.Entities:
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Year: 2007 PMID: 17581941 PMCID: PMC1951220 DOI: 10.1128/JCM.00015-07
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948