| Literature DB >> 2055120 |
E P Arnoldus1, I A Noordermeer, A C Peters, A K Raap, M Van der Ploeg.
Abstract
Nuclei isolated from normal human brain tissue, collected from six autopsies, were hybridized with a panel of nine satellite DNA probes specific for the centromeric regions of chromosomes 1, 6, 7, 10, 11, 17, 18, and the X and Y chromosomes. The results did not confirm the recently reported trisomy 7 and loss of sex chromosomes observed in metaphases obtained from normal brain tissue after short-term cultures; however, cells of all six brains displayed somatic pairing of the chromosome 17 centromeres in approximately 50% of the nuclei.Entities:
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Year: 1991 PMID： 2055120 DOI： 10.1159/000133092
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171