Literature DB >> 20524020

dockYard--a repository to assist modeling of protein-protein docking.

Pralay Mitra1, Debnath Pal.   

Abstract

In the absence of interlogs, building docking models is a time intensive task, involving generation of a large pool of docking decoys followed by refinement and screening to identify near native docking solutions. This limits the researcher interested in building docking methods with the choice of benchmarking only a limited number of protein complexes. We have created a repository called dockYard ( http://pallab.serc.iisc.ernet.in/dockYard ), that allows modelers interested in protein-protein interaction to access large volume of information on protein dimers and their interlogs, and also download decoys for their work if they are interested in building modeling methods. dockYard currently offers four categories of docking decoys derived from: Bound (native dimer co-crystallized), Unbound (individual subunits are crystallized, as well as the target dimer), Variants (match the previous two categories in at least one subunit with 100% sequence identity), and Interlogs (match the previous categories in at least one subunit with ≥ 90% or ≥ 50% sequence identity). The web service offers options for full or selective download based on search parameters. Our portal also serves as a repository to modelers who may want to share their decoy sets with the community.

Mesh:

Year:  2010        PMID: 20524020     DOI: 10.1007/s00894-010-0758-9

Source DB:  PubMed          Journal:  J Mol Model        ISSN: 0948-5023            Impact factor:   1.810


  31 in total

1.  BiGGER: a new (soft) docking algorithm for predicting protein interactions.

Authors:  P N Palma; L Krippahl; J E Wampler; J J Moura
Journal:  Proteins       Date:  2000-06-01

2.  A novel method for scoring of docked protein complexes using predicted protein-protein binding sites.

Authors:  Kay-Eberhard Gottschalk; Hani Neuvirth; Gideon Schreiber
Journal:  Protein Eng Des Sel       Date:  2004-03-08       Impact factor: 1.650

3.  Molecular surface recognition: determination of geometric fit between proteins and their ligands by correlation techniques.

Authors:  E Katchalski-Katzir; I Shariv; M Eisenstein; A A Friesem; C Aflalo; I A Vakser
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

4.  Clustering protein-protein docking predictions.

Authors:  W Tong; Z Weng
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2004

5.  On the multiple simultaneous superposition of molecular structures by rigid body transformations.

Authors:  R Diamond
Journal:  Protein Sci       Date:  1992-10       Impact factor: 6.725

6.  Infrastructure for the life sciences: design and implementation of the UniProt website.

Authors:  Eric Jain; Amos Bairoch; Severine Duvaud; Isabelle Phan; Nicole Redaschi; Baris E Suzek; Maria J Martin; Peter McGarvey; Elisabeth Gasteiger
Journal:  BMC Bioinformatics       Date:  2009-05-08       Impact factor: 3.169

7.  Structure of a diubiquitin conjugate and a model for interaction with ubiquitin conjugating enzyme (E2).

Authors:  W J Cook; L C Jeffrey; M Carson; Z Chen; C M Pickart
Journal:  J Biol Chem       Date:  1992-08-15       Impact factor: 5.157

8.  Differential ubiquitin binding of the UBA domains from human c-Cbl and Cbl-b: NMR structural and biochemical insights.

Authors:  Zi-Ren Zhou; Hong-Chang Gao; Chen-Jie Zhou; Yong-Gang Chang; Jing Hong; Ai-Xin Song; Dong-Hai Lin; Hong-Yu Hu
Journal:  Protein Sci       Date:  2008-07-02       Impact factor: 6.725

9.  3D-Garden: a system for modelling protein-protein complexes based on conformational refinement of ensembles generated with the marching cubes algorithm.

Authors:  Victor I Lesk; Michael J E Sternberg
Journal:  Bioinformatics       Date:  2008-03-07       Impact factor: 6.937

10.  Data growth and its impact on the SCOP database: new developments.

Authors:  Antonina Andreeva; Dave Howorth; John-Marc Chandonia; Steven E Brenner; Tim J P Hubbard; Cyrus Chothia; Alexey G Murzin
Journal:  Nucleic Acids Res       Date:  2007-11-13       Impact factor: 16.971

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  1 in total

Review 1.  Sampling and scoring: a marriage made in heaven.

Authors:  Sandor Vajda; David R Hall; Dima Kozakov
Journal:  Proteins       Date:  2013-08-19
  1 in total

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